UDPacetylglucosamine-dolichyl-phosphate acetylglucosamine-1-phosphate transferase

transfers N-acetylglucosamine 1-phosphate from UDP-N-acetylglucosamine to dolichyl phosphate, forming N-acetylglucosaminylpyrophosphoryldolichol

Also Known As:

Dol-P-P-GlcNAc synthase; GlcNAc-DP-1-phosphotransferase; N-acetylglucosamine-1-phosphate transferase; UDP-N-acetyl-D-glucosamine-dolichyl-phosphate N-acetyl-D-glucosaminephosphotransferase; UDP-acetylglucosamine-dolichol phosphate acetylglucosamine-1-phosphate transferase; dolichol pathway enzyme I; dolichol-P-dependent N-acetylglucosamine-1-phosphate transferase; UDP-GlcNAc-dolichyl-phosphate GlcNAc-1-phosphate transerase

Networked: 7 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Transferases: 6589
    - Phosphotransferases: 42769
      - Transferases (Other Substituted Phosphate Groups)
        UDPacetylglucosamine-dolichyl-phosphate acetylglucosamine-1-phosphate transferase: 7

Experts

1.	Hajjaran, Homa: 3 articles (01/2018 - 08/2014)
2.	Mirjalali, Hamed: 2 articles (05/2016 - 08/2014)
3.	Mohebali, Mehdi: 2 articles (05/2016 - 08/2014)
4.	Abadi, Alireza: 1 article (01/2018)
5.	Kheirandish, Farnaz: 1 article (01/2018)
6.	Moin-Vaziri, Vahideh: 1 article (01/2018)
7.	Niyyati, Maryam: 1 article (01/2018)
8.	Saberi, Reza: 1 article (01/2018)
9.	Taghipour, Niloofar: 1 article (01/2018)
10.	Ahmadpour, Niloofar Bavarsad: 1 article (05/2016)

Related Diseases

1.	Leishmaniasis 08/01/2014 - "Identification and phylogenetic relationship of Iranian strains of various Leishmania species isolated from cutaneous and visceral cases of leishmaniasis based on N-acetylglucosamine-1-phosphate transferase gene." 05/01/2016 - "The current study aimed to evaluate the inter- and intragenic diversities of Leishmania species isolated from patients with leishmaniasis in Fars Province, using PCR-based analyses and DNA sequencing of the N-acetylglucosamine-1-phosphate transferase (nagt) gene. "
2.	Vascular Calcification 04/15/2015 - "N-acetylglucosamine-1-Phosphate Transferase Suppresses Lysosomal Hydrolases in Dysfunctional Osteoclasts: A Potential Mechanism for Vascular Calcification."
3.	Cutaneous Leishmaniasis 01/01/2018 - "Identification of Leishmania species using N-acetylglucosamine-1-phosphate transferase gene in a zoonotic cutaneous leishmaniasis focus of Iran."
4.	Stuttering (Stammering) 02/25/2010 - "We identified a missense mutation in the N-acetylglucosamine-1-phosphate transferase gene (GNPTAB), which encodes the alpha and beta catalytic subunits of GlcNAc-phosphotransferase (GNPT [EC 2.7.8.15]), that was associated with stuttering in a large, consanguineous Pakistani family. "
5.	Neoplasms (Cancer) 01/01/1987 - "UDP-N-acetylglucosamine: lysosomal enzyme precursor N-acetylglucosamine-1-phosphate transferase activities in human ovarian tumor tissue and some transformed cell lines."

Related Drugs and Biologics

1.	DNA (Deoxyribonucleic Acid)
2.	Uridine Diphosphate (UDP)
3.	Phosphotransferases (Kinase)
4.	Hydrolases
5.	Enzyme Precursors (Zymogens)
6.	Acetylglucosamine