glyoxylate aminotransferase

various amino acids can serve as amino donors; with serine it is EC 2.6.1.45; best donors for rat liver & kidney enzyme are leucine & phenylalanine

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Assimos, Dean G: 1 article (01/2017)

Related Diseases

1.	Primary Hyperoxaluria (Oxaluria, Primary) 12/01/1991 - "Mistargeting of peroxisomal L-alanine:glyoxylate aminotransferase to mitochondria in primary hyperoxaluria patients depends upon activation of a cryptic mitochondrial targeting sequence by a point mutation." 01/01/2017 - "Re: Use of Polymer Conjugates for the Intraperoxisomal Delivery of Engineered Humanalanine:Glyoxylate Aminotransferase as a Protein Therapy for Primary Hyperoxaluria Type I."
2.	Primary hyperoxaluria type 1 12/01/1991 - "In approximately one-third of primary hyperoxaluria type 1 patients, disease is associated with a unique protein sorting defect in which hepatic L-alanine:glyoxylate aminotransferase (AGT; EC 2.6.1.44), which is normally peroxisomal, is mistargeted to mitochondria. " 01/01/1996 - "Energy-dependent degradation of a mutant serine: pyruvate/alanin: glyoxylate aminotransferase in a primary hyperoxaluria type 1 case."
3.	Hyperoxaluria (Oxaluria) 08/15/1990 - "Human liver L-alanine-glyoxylate aminotransferase: characteristics and activity in controls and hyperoxaluria type I patients using a simple spectrophotometric method."

Related Drugs and Biologics

1.	Alanine (L-Alanine)
2.	Pyruvic Acid (Pyruvate)
3.	Serine (L-Serine)
4.	Proteins (Proteins, Gene)
5.	Polymers

Related Therapies and Procedures

1.	Therapeutics