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20682-S

structure

Also Known As:

20682 S; 3,14-dihydroxy-6-oxo-N-cyclopropylmethylmorphinan methanesulfonate; S 20682; S-20682

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

1.	Respiratory Insufficiency (Respiratory Failure) 09/01/1979 - "The latent side effects (respiratory depression and fall in blood pressure) and the acute toxicity of 20681-S and 20682-S, were less than those of reference narcotic antagonists or of narcotic antagonist analgesics." 01/01/1983 - "Prevention of late fentanyl-induced respiratory depression after the injection of opiate antagonists naltrexone and S-20682: comparison with naloxone." 01/01/1983 - "Compared with naloxone, two opiate antagonists (naltrexone and S-20682) were tested in the intact dog in order to reverse respiratory depression, induced by fentanyl 50 micrograms kg-1 i.v. Respiratory rate and arterial blood-gases were measured at 5, 30, 60, 120, 180 and 240 min after the additional i.v. injection of the antagonist (1 microgram kg-1). "
2.	Bradycardia 01/01/1983 - "Compared to the control-awake situation, diprenorphine and S-20682 induced hypotension (maximum fall 15%), bradycardia (maximum 12%) and bradypnoea (maximum 25%). "

Related Drugs and Biologics

1.	Opiate Alkaloids
2.	Narcotic Antagonists (Opioid Antagonists)
3.	Naltrexone (ReVia)
4.	Naloxone (Narcan)
5.	Gases
6.	Fentanyl (Sublimaze)
7.	Diprenorphine
8.	Analgesics (Analgesic Drugs)
9.	20681-S

Related Therapies and Procedures

1.	Controlled Hypotension