arborinine

01/01/2021 - "Overall, we demonstrated the potential of arborinine as an effective treatment for gastric cancer and adriamycin-resistant gastric cancer."
01/01/2021 - "Furthermore, it was found that arborinine suppressed the epithelial-mesenchymal transition of gastric cancer cell line SGC-7901 and adriamycin-resistant gastric cancer cell line SGC-7901/ADR in a dose-dependent manner. "
01/01/2021 - "Arborinine, a potential LSD1 inhibitor, inhibits epithelial-mesenchymal transition of SGC-7901 cells and adriamycin-resistant gastric cancer SGC-7901/ADR cells."

01/01/2021 - "The in vivo antitumor study further indicated that arborinine can significantly reduce the growth of tumors both in SGC-7901 and SGC-7901/ADR xenograft mouse models. "
02/15/2022 - "Our results demonstrated that arborinine treatment significantly inhibited the cell proliferation and tumor growth of SKOV3 in a dose-dependent manner. "
02/15/2022 - "The tumor-bearing mouse model was applied to assess the anti-tumor effect of arborinine in vivo. "
02/15/2022 - "Arborinine has been known as a broad-spectrum anti-tumor agent due to it possesses a potent cytotoxic effect on various cancer cells. "
01/01/2022 - "Overexpression of UBE2O abrogated cancer-inhibitory effect of Arborinine. "

12/01/2018 - "Taken together, our data provide important insights into the molecular mechanism of arborinine's anticancer activity, supporting its potential use for treating cervical cancer."
12/01/2018 - "Anticancer activity of arborinine from Glycosmis parva leaf extract in human cervical cancer cells."
12/01/2018 - "In this study, we demonstrate that arborinine, a major acridone alkaloid in the EtOAc fraction, decreased proliferation and was strongly cytotoxic to HeLa cervical cancer cells without significantly affecting normal cells. "

02/15/2022 - "Arborinine may serve as a potential drug candidate for developing new strategies for ovarian cancer treatment."
02/15/2022 - "Arborinine suppresses ovarian cancer development through inhibition of LSD1."

01/01/2006 - "There was no significant variation on the necrosis rate of the cells treated with arborinine or any change on their viability or function values in the absence of mitogenic stimulus."