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tartronate-semialdehyde synthase
Also Known As:
glyoxylate carbo-ligase; glyoxylate carboligase
Networked:
9
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Enzymes and Coenzymes: 1
Enzymes: 152586
Lyases: 637
Carbon-Carbon Lyases
Carboxy-Lyases: 620
tartronate-semialdehyde synthase: 9
Related Diseases
1.
Primary Hyperoxaluria (Oxaluria, Primary)
05/01/1986 - "
Mitochondrial damage and the subcellular distribution of 2-oxoglutarate:glyoxylate carboligase in normal human and rat liver and in the liver of a patient with primary hyperoxaluria type I.
"
02/01/1972 - "
Primary hyperoxaluria with normal alpha-ketoglutarate: glyoxylate carboligase activity.
"
04/01/1967 - "
Deficiency of 2-oxo-glutarate: glyoxylate carboligase activity in primary hyperoxaluria.
"
05/01/1986 - "
The subcellular distribution of 2-oxoglutarate:glyoxylate carboligase was investigated in a normal human liver, a liver from a patient with pyridoxine-resistant primary hyperoxaluria type I and rat livers subjected to various degrees and types of trauma.
"
03/01/1991 - "
The alpha-ketoglutarate glyoxylate carboligase and serine pyruvate transoxylase activities in the patient's liver had markedly decreased, indicating type I primary hyperoxaluria.
"
2.
Wounds and Injuries (Trauma)
05/01/1986 - "
The subcellular distribution of 2-oxoglutarate:glyoxylate carboligase was investigated in a normal human liver, a liver from a patient with pyridoxine-resistant primary hyperoxaluria type I and rat livers subjected to various degrees and types of trauma.
"
3.
Thiamine Deficiency
01/01/1981 - "
The effect of thiamine deficiency on glyoxylic acid metabolism in mice and rats was investigated to determine whether the vitamin deficiency results in gross effects on glyoxylate levels via an alteration in the activity of alpha-ketoglutarate:glyoxylate carboligase.
"
4.
Starvation
11/02/1976 - "
Glyoxylate carboligase was also stimulated by light and inhibited during nitrogen-starvation but only partially recovered activity after reintroduction of nitrate.
"
5.
Magnesium Deficiency (Deficiency, Magnesium)
06/01/1993 - "
Magnesium deficiency altered the glyoxylate metabolism in the liver and kidney mitochondria by significantly decreasing glyoxylate oxidation (by 26 per cent in liver and 17 per cent in kidney) and activity of alpha-ketoglutarate:glyoxylate carboligase enzyme (by 35 per cent in liver and 27 per cent in kidney) in the experimental animals.
"
Related Drugs and Biologics
1.
Ketoglutaric Acids (Ketoglutaric Acid)
2.
glyoxylic acid (glyoxylate)
3.
Pyruvic Acid (Pyruvate)
4.
Serine (L-Serine)
5.
Pyridoxine (Pyridoxin)
6.
Nitrogen
7.
Nitrates
8.
Glutarates
9.
Enzymes
10.
adipic acid (adipate)
Related Therapies and Procedures
1.
Kidney Transplantation