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doridosine
isolated from aqueous extracts of digestive glands of Anisodoris nobilis; structure
Also Known As:
1-methylisoguanosine; N(1)-methylisoguanosine; Adenosine, N,6-didehydro-1,2,3,6-tetrahydro-1-methyl-2-oxo-
Networked:
2
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Purines: 651
Purine Nucleosides: 360
Guanosine: 1156
doridosine: 2
Nucleic Acids, Nucleotides, and Nucleosides: 1
Nucleosides: 6847
Purine Nucleosides: 360
Guanosine: 1156
doridosine: 2
Ribonucleosides: 49
Guanosine: 1156
doridosine: 2
Related Diseases
1.
Hypotension (Low Blood Pressure)
01/11/1980 - "
Doridosine produces prolonged hypotension and bradycardia in anesthetized rats, decreases the rate and the amplitude of contraction of guinea pig atria in vitro, and causes the heart rate in anesthetized mice to be reduced by 50 percent for many hours after which the animals recover completely.
"
10/19/1993 - "
Doridosine, an adenosine analogue, causes, in vivo, hypotension, reduction of heart rates, muscle relaxation and anti-inflammatory effects through adenosine A1 and A2 receptors.
"
2.
Bradycardia
01/11/1980 - "
Doridosine produces prolonged hypotension and bradycardia in anesthetized rats, decreases the rate and the amplitude of contraction of guinea pig atria in vitro, and causes the heart rate in anesthetized mice to be reduced by 50 percent for many hours after which the animals recover completely.
"
Related Drugs and Biologics
1.
Adenosine (Adenocard)