ribosephosphate isomerase

Also Known As:

D-ribose-5-phosphate ketol-isomerase; RpiB protein, E coli; phosphoriboisomerase; ribose phosphate isomerase; ribose-5-phosphate isomerase; ribosephosphate isomerase A; ribosephosphate isomerase B; ribosephosphate isomerase B, E coli

Networked: 15 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Isomerases: 463
    - Intramolecular Oxidoreductases
      - Aldose-Ketose Isomerases
        ribosephosphate isomerase: 15

Experts

1.	Chou, Yu-Ting: 3 articles (01/2019 - 07/2015)
2.	Lu, Jeng-Wei: 3 articles (01/2019 - 07/2015)
3.	Wang, Horng-Dar: 3 articles (01/2019 - 07/2015)
4.	Yuh, Chiou-Hwa: 3 articles (01/2019 - 07/2015)
5.	Ciou, Shih-Ci: 2 articles (01/2019 - 07/2015)
6.	Kaur, Preet Kamal: 2 articles (01/2016 - 08/2014)
7.	Singh, Sushma: 2 articles (01/2016 - 08/2014)
8.	Guo, Jizheng: 1 article (09/2020)
9.	Hu, Weiguo: 1 article (09/2020)
10.	Lei, Qun-Ying: 1 article (09/2020)

Related Diseases

1.	Hepatocellular Carcinoma (Hepatoma) 01/01/2019 - "Our recent study demonstrated that ribose-5-phosphate isomerase (RPIA), a key regulator of the PPP, regulates hepatoma cell proliferation and colony formation. " 07/01/2015 - "Here, we report that human ribose-5-phosphate isomerase A (RPIA) plays a role in human hepatocellular carcinoma (HCC). "
2.	Leukoencephalopathies 10/01/2018 - "Whole-exome sequencing demonstrated 2 mutations in the ribose-5-phosphate isomerase gene, RPIA, in a child with neonatal onset leukoencephalopathy and psychomotor delays. " 01/01/2011 - "Deficiency of ribose-5-phosphate isomerase has been described in one patient who suffered from a progressive leukoencephalopathy and developmental delay. " 04/01/2004 - "Ribose-5-phosphate isomerase deficiency: new inborn error in the pentose phosphate pathway associated with a slowly progressive leukoencephalopathy." 04/01/2004 - "The present article describes the first patient with a deficiency of ribose-5-phosphate isomerase (RPI) (Enzyme Commission number 5.3.1.6) who presented with leukoencephalopathy and peripheral neuropathy. "
3.	Colorectal Neoplasms (Colorectal Cancer) 07/17/2022 - "Ribose-5-phosphate isomerase A (RPIA) regulates tumorigenesis in liver and colorectal cancer. " 01/01/2018 - "Identification of a noncanonical function for ribose-5-phosphate isomerase A promotes colorectal cancer formation by stabilizing and activating β-catenin via a novel C-terminal domain." 09/01/2020 - "Arginine methylation of ribose-5-phosphate isomerase A senses glucose to promote human colorectal cancer cell survival."
4.	Carcinogenesis 01/01/2018 - "Deregulation of ribose-5-phosphate isomerase A (RPIA) in the pentose phosphate pathway (PPP) is known to promote tumorigenesis in liver, lung, and breast tissues. " 07/17/2022 - "Ribose-5-phosphate isomerase A (RPIA) regulates tumorigenesis in liver and colorectal cancer. "
5.	Visceral Leishmaniasis (Kala Azar) 01/01/2016 - "Ribose-5-phosphate isomerase B from Leishmania donovani (LdRpiB) is one of the potential drug targets against visceral leishmaniasis. " 08/01/2014 - "Ribose-5-phosphate isomerase B (RpiB), a crucial enzyme of pentose phosphate pathway, was proposed to be a potential drug target for visceral leishmaniasis. "

Related Drugs and Biologics

1.	Enzymes
2.	Catenins
3.	TOR Serine-Threonine Kinases
4.	Facilitative Glucose Transport Proteins (Glucose Transporter)
5.	Proto-Oncogene Proteins c-akt (Protein Kinase B)
6.	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)
7.	Symporters
8.	Vacuolar Proton-Translocating ATPases (V-Type ATPase)
9.	Racemases and Epimerases (Epimerases and Racemases)
10.	Glutathione Disulfide (GSSG)