pantetheinase (pantetheine hydrolase)

11/01/2015 - "Tissue pantetheinase, encoded by the VNN1 gene, regulates response to stress, and previous studies have shown that VNN genes contribute to the susceptibility to malaria. "
03/19/2007 - "These studies suggest that pantetheinase is critical for the host response to malaria."
11/01/2015 - "Therefore, serum pantetheinase level regulates erythrocyte life span and modulates the risk of developing complicated malaria. "
11/01/2015 - "Herein, we evaluated the role of pantetheinase on erythrocyte homeostasis and on the development of malaria in patients and in a new mouse model of pantetheinase insufficiency. "
11/01/2015 - "Serum pantetheinase/vanin levels regulate erythrocyte homeostasis and severity of malaria."

10/01/2013 - "Vanin-1 is an epithelial pantetheinase, which regulates intestinal inflammation in mouse. "
09/20/2013 - "This review delineates the characteristics of the pantetheinase/vanin gene family and how they affect inflammation. "
01/01/2007 - "Vanin-1 is a membrane-anchored pantetheinase that controls tissue inflammation. "
09/20/2013 - "Linkage between coenzyme a metabolism and inflammation: roles of pantetheinase."
01/01/2018 - "Pantetheinase, a glycosylphosphatidylinositol (GPI) anchored enzyme, overexpresses in intestine, liver, and kidney with various biological functions such as its linkage to the inflammation and some metabolic diseases. "

08/01/2010 - "In mice, loss of pantetheinase activity causes susceptibility to infection with Plasmodium chabaudi AS. "
01/01/2017 - "These findings suggest that the metabolic pathway catalyzed by VNN1 pantetheinase plays a suppressive role in IAV infection in the respiratory tract, especially in severe conditions under hypercytokinemia."
11/01/2015 - "Therefore, scoring pantetheinase in serum may serve as a severity marker in malaria infection. "
08/01/2010 - "This study highlights the in vivo action of cysteamine against Plasmodium and provides further evidence for the involvement of pantetheinase in host response to this infection."
08/01/2011 - "Genetic analyses in mouse model of malaria show that inactivation of the enzyme pantetheinase (Char9 locus) causes susceptibility to blood-stage infection. "

01/01/2016 - "Previous studies in mice have indicated that vanin-1, a member of the vanin protein family with pantetheinase activity, is possibly involved in neointima formation. "

09/25/2020 - "Moreover, with the probe we have observed that pantetheinase is significantly increased in the tissues of mouse inflammatory models as well as in the intestines of mice with inflammatory bowel disease. "
12/25/2006 - "Thus, the Vanin-1/pantetheinase activity might be a new target for therapeutic intervention in inflammatory bowel disease."