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oxiconazole (Salongo)

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RN given refers to parent cpd(Z)-isomer; structure given in first source

Also Known As:

Salongo; (Z)-1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)-O-(2,4-dichlorobenzyl) ethanone oxime nitrate; Bioglan brand of oxiconazole nitrate; Biosarto brand of oxiconazole nitrate; Fonx; Glaxo Wellcome brand of oxiconazole nitrate; GlaxoSmithKline brand of oxiconazole nitrate; Gyno-Myfungar; Myfungar; Oceral; Oxistat; Oxizole; RO-13-8996; Sgd 301-76; Siegfried brand of oxiconazole nitrate; Stiefel brand of oxiconazole nitrate; Yamanouchi brand of oxiconazole nitrate; oxiconazole mononitrate, (Z)-isomer; oxiconazole nitrate; oxyconazole; Ethanone, 1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)-, O-((2,4-dichlorophenyl)methyl)oxime, (Z)-, mononitrate

Networked: 25 relevant articles (4 outcomes, 8 trials/studies)

Relationship Network

Drug Context: Research Results

Heterocyclic Compounds: 60
- 1-Ring Heterocyclic Compounds
  - Azoles: 413
    - Imidazoles: 107
      - oxiconazole: 25

Experts

1.	Cárdenes, Délia: 1 article (08/2015)
2.	Giusiano, Gustavo: 1 article (08/2015)
3.	Tur-Tur, Cristina: 1 article (08/2015)
4.	Rojas, Florencia: 1 article (08/2015)
5.	Carrillo-Muñoz, Alfonso Javier: 1 article (08/2015)
6.	Korshunov, G V: 1 article (05/2014)
7.	Gladilin, G P: 1 article (05/2014)
8.	NIkitina, V V: 1 article (05/2014)
9.	Zakharova, N B: 1 article (05/2014)
10.	Kircik, Leon H: 1 article (11/2013)

Related Diseases

1.	Dermatomycoses (Dermatophytosis) 01/01/1987 - "One daily application of oxiconazole cream is sufficient for treating dermatomycoses." 07/01/2000 - "Evaluation of clinical efficacy and safety of once daily topical administration of 1% oxiconazole cream and lotion in dermatophytosis : an open label, non comparative multicentre study." 01/01/1987 - "A single daily application of oxiconazole cream was shown, in a double-blind, randomized, multicentric study, to be effective in treating various dermatomycoses as well as erythrasma. " 01/01/1984 - "A study to compare the efficacy of miconazole 2% cream with the oxiconazole 1% cream for the treatment of dermatophytosis was conducted in a group of 48 patients. " 10/01/1987 - "[Oxiconazole in dermatomycosis--a double-blind, randomized therapy compared with bifonazole]."
2.	Tinea Pedis (Athlete's Foot) 07/01/1994 - "Oxiconazole nitrate lotion, 1 percent: an effective treatment for tinea pedis." 01/01/1991 - "In plantar-type tinea pedis caused primarily by T rubrum, once-daily oxiconazole cream resulted in a mycologic cure in 76% of patients. " 01/01/1991 - "Oxiconazole nitrate (1%) cream became available in the United States in 1989 for the once-daily treatment of tinea pedis, tinea cruris, and tinea corporis. " 08/01/1989 - "The minimal inhibition concentration (MIC) to Epidermophyton floccosum and Candida guilliermondi are 1 microgram/ml and 0.5 microgram/ml. The cure rate of 2% cream of oxiconazole in 124 cases of tinea corporis and tinea cruris is 90.3%, and in 88 cases of tinea pedis, 89.78%." 08/01/1989 - "A new antimycotic imicazole drug, oxiconazole, used both in vitro and in vivo in the treatment of 212 cases of tinea corporis, tinea cruris and tinea pedis is reported. "
3.	Erythrasma 01/01/1987 - "A single daily application of oxiconazole cream was shown, in a double-blind, randomized, multicentric study, to be effective in treating various dermatomycoses as well as erythrasma. "
4.	Tinea (Ringworm) 01/01/1991 - "Oxiconazole nitrate (1%) cream became available in the United States in 1989 for the once-daily treatment of tinea pedis, tinea cruris, and tinea corporis. " 08/01/1989 - "The minimal inhibition concentration (MIC) to Epidermophyton floccosum and Candida guilliermondi are 1 microgram/ml and 0.5 microgram/ml. The cure rate of 2% cream of oxiconazole in 124 cases of tinea corporis and tinea cruris is 90.3%, and in 88 cases of tinea pedis, 89.78%." 08/01/1989 - "A new antimycotic imicazole drug, oxiconazole, used both in vitro and in vivo in the treatment of 212 cases of tinea corporis, tinea cruris and tinea pedis is reported. " 07/01/2000 - "The clinical efficacy and safety of once daily topical administration of 1% oxiconazole cream and lotion was assessed in an open label, non comparative trial in tinea cruris, tinea corporis and tinea pedis patients. " 01/01/1991 - "Applied once daily for four weeks in the treatment of tinea pedis or for two weeks in the treatment of tinea corporis, tinea cruris, and tinea versicolor, 1% oxiconazole cream has produced mycologic and clinical cures in at least 80% of patients. "
5.	Candidiasis (Moniliasis) 04/01/1985 - "[Treatment of vaginal candidiasis with a new imidazole derivative, oxiconazole]." 01/01/1984 - "Oxiconazole in the treatment of vaginal candidiasis: single dose versus 3-day treatment with econazole." 01/01/1984 - "Fifty-one women with vaginal candidiasis were included in an open randomized study to compare the efficacy and local tolerance of a single-dose treatment with 600 mg oxiconazole (one vaginal tablet) with that of a 3-day treatment with econazole (one 150 mg ovule daily). "

Related Drugs and Biologics

1.	Miconazole (Monistat)
2.	terbinafine (Lamisil)
3.	naftifine (naftifine hydrochloride)
4.	Econazole
5.	oxiconazole (Salongo)
6.	Clotrimazole (Lotrimin)
7.	bifonazole
8.	Vaginal Creams, Foams, and Jellies (Vaginal Tablet)
9.	Tolnaftate (Ting)
10.	Nitric Oxide (Nitrogen Monoxide)

Related Therapies and Procedures

1.	Topical Administration