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phenylacetylglycine

Also Known As:

phenaceturic acid; N-(phenylacetyl)glycine

Networked: 17 relevant articles (1 outcomes, 1 trials/studies)

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Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Amino Acids: 30675
  - Glycine: 5151
    - phenylacetylglycine: 17

Experts

1.	Holmes, Elaine: 4 articles (09/2011 - 07/2008)
2.	Utzinger, Jürg: 4 articles (09/2011 - 07/2008)
3.	Li, Jia V: 3 articles (01/2021 - 07/2008)
4.	Wang, Yulan: 3 articles (09/2011 - 07/2008)
5.	Keiser, Jennifer: 2 articles (09/2011 - 07/2008)
6.	Saric, Jasmina: 2 articles (09/2011 - 07/2008)
7.	Singer, Burton H: 2 articles (05/2010 - 12/2009)
8.	Xiao, Shu-Hua: 2 articles (05/2010 - 12/2009)
9.	Xue, Jian: 2 articles (05/2010 - 12/2009)
10.	Cai, Yuan: 1 article (01/2022)

Related Diseases

1.	Neurodegenerative Diseases (Neurodegenerative Disease) 01/01/2015 - "The association between hippurate excretion and antioxidant biomarkers along with the relationship between phenylacetylglycine excretion and oxidant biomarkers suggests that the long-term consumption of a Med + CoQ diet could be beneficial for healthy aging and a promising challenge in the prevention of processes related to chronic oxidative stress, such as cardiovascular and neurodegenerative disease."
2.	Thrombosis (Thrombus) 01/01/2020 - "Functional and genetic engineering studies with human commensals, coupled with microbial colonization of germ-free mice, showed the microbial porA gene facilitates dietary phenylalanine conversion into phenylacetic acid, with subsequent host generation of PAGln and phenylacetylglycine (PAGly) fostering platelet responsiveness and thrombosis potential. "
3.	Infections 09/19/2011 - "mansoni infection, among which hippurate, phenylacetylglycine (PAG) and 2-oxoadipate were particularly robust with regard to disease progression. " 07/02/2008 - "The main changes in the urine metabolic profile started at day 8 post-infection, characterized by increased relative concentrations of trimethylamine and phenylacetylglycine and lower levels of 2-ketoisocaproate and showed differentiation over the course of the infection. " 12/01/2009 - "americanus infection, manifested in the alterations of microbial-mammalian cometabolites, including phenylacetylglycine, p-cresol glucuronide, 4-hydroxy-3-methyl-phenylpropionic acid, hippurate, 4-hydroxyphenylactate, and dimethylamine. "
4.	Fibrosis (Cirrhosis) 01/01/2021 - "Urinary levels of phenylacetylglycine (a host-bacterial cometabolite) and tauro-β-muricholic acid were higher in the Ov+ group, which coexisted with hepatic and mild kidney fibrosis. " 01/01/2017 - "The results showed good discrimination between patients with cirrhosis (n = 52) and healthy controls (n = 17) (R2X = 0.66, R2Y = 0.47, Q2Y = 0.31, sensitivity-60 %, specificity-100 %) as the cirrhosis group had higher 1-methylnicotinamide with lower hippurate, acetate, phenylacetylglycine and N-methyl nicotinic acid levels. "
5.	Hypoxia (Hypoxemia) 01/01/2022 - "We subsequently constructed an interaction network of mRNAs and metabolites related to hypoxia, such as guanosine-3', 5'-cyclic monophosphate, Gly-Tyr, and phenylacetylglycine. " 12/01/2015 - "Metabolomics urinalysis showed alterations in TCA cycle metabolites (citrate, α-ketoglutarate), cell membrane metabolism (choline), gut micro-flora metabolism (hippurate, phenylacetylglycine), and others (N-acetyl glutamate, creatine, taurine) in response to hypobaric hypoxia. "

Related Drugs and Biologics

1.	hippuric acid
2.	Biomarkers (Surrogate Marker)
3.	Oxidants (Oxidizing Agents)
4.	Antioxidants
5.	Phenylalanine (L-Phenylalanine)
6.	phenylacetic acid (phenylacetate)
7.	Citric Acid (Citrate)
8.	Glucuronides
9.	Creatinine
10.	Alanine (L-Alanine)