cholesteryl linoleate

RN given refers to (Z,Z)-isomer

Also Known As:

CLOH; cholesteryl linoleate, (E,E)-isomer; cholesteryl linoleate, (E,Z)-isomer; cholesteryl linoleate, (Z,E)-isomer; cholesteryl linolelaidate; cholesteryl trans-9-trans-12-octadecadienoate; (Z,Z)-(3 beta)-cholest-5-en-3-ol, 9,12- octadecadienoate

Networked: 13 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Desharnais, Robert: 1 article (01/2015)
2.	Faull, Kym F: 1 article (01/2015)
3.	Ma, Daniel C: 1 article (01/2015)
4.	Porter, Edith: 1 article (01/2015)
5.	Yoon, Alexander J: 1 article (01/2015)
6.	Zemanick, Edith T: 1 article (01/2015)
7.	Kim, Se-Hwa: 1 article (02/2013)
8.	Lee, Eun-Soo: 1 article (02/2013)
9.	Lee, Tae Geol: 1 article (02/2013)
10.	Moon, Dae Won: 1 article (02/2013)

Related Diseases

1.	Scrapie 08/04/2011 - "Of interest, oral pravastatin administration to Scrapie-infected mice, was associated with a significant reduction of cerebral free cholesterol (FC) along with a concomitant further increase of the CE pool, which included increased amounts of both cholesteryl-linoleate and cholesteryl-arachidonate. "
2.	Multiple Sclerosis 08/01/1968 - "Further studies on platelet adhesiveness and serum cholesteryl linoleate levels in multiple sclerosis."
3.	Atherosclerosis 11/01/1975 - "Rabbits with cholesteryl linoleate/oleate ratios below 0.6 seemed to run a greater risk of developing atherosclerosis. " 11/01/1975 - "No serious aorta atherosclerosis was found in rabbits with a cholesteryl linoleate/oleate ratio higher than 0.6, although no correlation was found between the atherosclerosis indices and these ratios at values lower than 0.6. " 08/01/2012 - "Metabolism of CEs is characterized by recurrent hydrolysis and esterification as part of the CE cycle; however, since recombinant 15-lipoxygenase (15-LO) was shown to oxidize cholesteryl linoleate of LDL, there has been interest in CE oxidation, particularly in the context atherogenesis. " 02/01/2013 - "We found that the ratio of cholesteryl palmitate (Ch-PA) to cholesteryl oleate (Ch-OA) increased by approximately 99% (p = 0.02) as atherosclerosis progressed, whereas the ratios of cholesteryl linoleate (p = 0.09) and cholesteryl stearate (p = 0.22) to Ch-OA did not change significantly. "
4.	Atherosclerotic Plaque (Atheroma) 12/01/1998 - "Cholesteryl linoleate hydroperoxide (CLOOH) and hydroxide (CLOH) are present in human atheroma. "
5.	Iron Overload 01/01/2006 - "An inverse relationship between the cholesteryl linoleate/cholesteryl oleate ratio (CL/CO) and the degree of clinical severity suggested that the CL/CO ratio is an index of damaged lipoproteins and could be used as a pathologic marker of underlying iron overload. "

Related Drugs and Biologics

1.	Pravastatin (Pravachol)
2.	Cholesterol
3.	cholesteryl arachidonate
4.	LDL Lipoproteins (beta Lipoproteins)
5.	oxidized low density lipoprotein
6.	Lipoproteins (Lipoprotein)
7.	cholesteryl linoleate
8.	cholesteryl oleate
9.	Oleic Acid (Oleate)
10.	Stearates