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nopaline synthase
forms N(2)-(1,3-dicarboxypropyl)arginine from NADPH, alpha-ketoglutarate & arginine; classified by analog with reverse reaction for EC 1.5.1.11
Networked:
10
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Enzymes and Coenzymes: 1
Enzymes: 152586
Oxidoreductases: 13671
Oxidoreductases Acting on CH-NH2 Group Donors
Amino Acid Oxidoreductases
nopaline synthase: 10
Experts
1.
Brunner, Amy M
: 1 article (04/2006)
2.
Ma, Caiping
: 1 article (04/2006)
3.
Meilan, Richard
: 1 article (04/2006)
4.
Skinner, Jeffrey S
: 1 article (04/2006)
5.
Strauss, Steven H
: 1 article (04/2006)
6.
Wei, Hao
: 1 article (04/2006)
Related Diseases
1.
Neoplasms (Cancer)
01/01/1985 - "
The Agrobacterium tumor-inducing (Ti) plasmid pTiT37 encodes nopaline synthase (NOS) gene (nos) with eukaryotic promoter elements that is expressed in transformed plant cells but not in the bacterial host.
"
01/01/1983 - "
Treatment of the tumor line with the in vivo demethylating drug 5-azacytidine at a concentration of 3 X 10(-5) M, resulted in the demethylation of, on average, one copy of the nopaline synthase gene per cell.
"
01/01/1983 - "
The FT37/1 tumor line induced by Agrobacterium tumefaciens on flax epicotyls contains 22-24 copies of the T-DNA encoded nopaline synthase gene per cell.
"
07/01/1988 - "
The isopentenyltransferase (ipt) gene associated with cytokinin biosynthesis in plants was cloned from a tumor-inducing plasmid carried by Agrobacterium tumefaciens and placed under the control of promoters of differing activities, the cauliflower mosaic virus 35S promoter and the nopaline synthase promoter.
"
09/01/1986 - "
Analysis of poly(A)(+) RNA isolated from the transformed tumor tissue demonstrated the following: (1) a single polyadenylated transcript, 2700 bp in length, was transcribed from the chimaeric gene; (2) the transcription was initiated at the published start site of the nopaline synthase gene; (3) the hGH polyadenylation site was not used for processing of the 3' end; only the poly(A) addition site of the nopaline synthase gene was recognized, (4) no splicing of the hGH introns could be detected.
"
2.
Infections
11/01/1986 - "
rhizogenes strain A4 containing the resident Ri plasmid plus a vector with the nopaline synthase marker, we found that up to 50% of the hairy roots resulting from the infection of alfalfa or tomato synthesized nopaline.
"
09/01/1999 - "
Tomato bushy stunt virus (TBSV) cDNA, positioned between a modified cauliflower mosaic virus 35S promoter and the hepatitis delta virus antigenomic ribozyme with a downstream nopaline synthase gene polyadenylation signal, established infections upon rub-inoculation of plants with intact plasmids.
"
07/01/1995 - "
The protocol is based on infection of cotyledon explants of 5-d-old seedlings with an Agrobacterium tumefaciens strain LBA4404 carrying a disarmed binary vector pTOK/BKS-1. The T-DNA region of this binary vector contains the nopaline synthase/neomycin phosphotransferase II (nptII) chimeric gene for kanamycin resistance and the cauliflower mosaic virus 35S/coat protein gene of tobacco mosaic virus L (TMV-L) chimeric gene.
"
3.
Wounds and Injuries (Trauma)
03/01/1990 - "
Nopaline synthase promoter is wound inducible and auxin inducible.
"
4.
Infertility (Sterility)
04/01/2006 - "
& Gray) homolog of the floral homeotic gene LEAFY (PTLF), which could be used to impart male and female flower sterility, to that of three candidate attenuator-gene promoters: the cauliflower mosaic virus (CaMV) 35S basal promoter, the CaMV 35S basal promoter fused to the TMV omega element and the nopaline synthase (NOS) promoter.
"
Related Drugs and Biologics
1.
T-DNA
2.
Kanamycin Kinase
3.
Complementary DNA (cDNA)
4.
Catalytic RNA (Ribozymes)
5.
Messenger RNA (mRNA)
6.
Proteins (Proteins, Gene)
7.
Poly A
8.
Indoleacetic Acids (Auxin)
9.
Elements
10.
Cytokinins