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3,3',5,5'-tetramethylbenzidine

Also Known As:
3,3',5,5'-TMP; tetramethyl benzidine; tetramethylbenzidine dihydrochloride; 3,3',5,5'-tetramethyl(1,1'-biphenyl)-4,4'-diamine
Networked: 14 relevant articles (2 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Wang, Jing: 2 articles (10/2020 - 12/2017)
2. Li, Xianming: 1 article (08/2022)
3. Wu, Peng: 1 article (08/2022)
4. Xie, Ya-Ni: 1 article (08/2022)
5. Ye, Peiqi: 1 article (08/2022)
6. Chi, Bin: 1 article (10/2020)
7. Gao, Haiqing: 1 article (10/2020)
8. Li, Ling: 1 article (10/2020)
9. Lin, Caixue: 1 article (10/2020)
10. Tian, Feng: 1 article (10/2020)

Related Diseases

1. Neoplasms (Cancer)
08/09/2023 - "The CD63 aptamer, which can specifically recognize and capture tumor-derived exosomes, enhanced the peroxidase activity of the hybrid nanozyme and helped to catalyze the 3,3',5,5'-tetramethylbenzidine (TMB)-H2O2 system to generate a stronger colorimetric signal, with its surface modification on the hybrid nanozyme. "
01/01/2014 - "By synergistically integrating highly catalytically active Pt NPs and MNPs on GO whose frameworks possess high substrate affinity, the nanohybrid is able to achieve up to a 30-fold higher maximal reaction velocity (V(max)) compared to that of free GO for the colorimetric reaction of the peroxidase substrate, 3,3',5,5'-tetramethylbenzidine (TMB), and enable rapid detection of target cancer cells. "
10/30/2020 - "The reason is that the Fe2+/Fe3+ in Fe-MOF interact with the rich H2O2 in cancer cells to generate hydroxyl radicals (ċOH), which is proved by the color of the solution of 3,3',5,5'-tetramethylbenzidine turning blue. "
10/01/2023 - "Here, peroxidase (POD)-like RuTe2 nanozyme with the immobilization of glucose oxidase (GOx) and allochroic 3,3',5,5'-tetramethylbenzidine (TMB) molecule have been synthesized to construct RuTe2 -GOx-TMB nanoreactors (RGT NRs) as cascade reaction systems for tumor-specific and self-replenishing cancer therapy. "
01/01/2023 - "In the tumor microenvironment, Ir nanozymes can act as logic control systems to trigger chromogenic reaction amplification of 3,3',5,5'-tetramethylbenzidine (TMB) for tumor-specific PTT, whereas in normal brain tissues, they scavenge reactive oxygen species (ROS) generated by poor therapy and function as protective agents. "
2. Infections
3. Photosensitivity Disorders (Photodermatitis)
4. Melanoma (Melanoma, Malignant)
5. Dehydration (Water Stress)

Related Drugs and Biologics

1. Peroxidase (Myeloperoxidase)
2. Dioctyl Sulfosuccinic Acid (DOSS)
3. DONS
4. Chlorophyll Binding Proteins
5. Protective Agents
6. Hydroxyl Radical
7. Reactive Oxygen Species (Oxygen Radicals)
8. Apolipoprotein A-I (Apolipoprotein A1)
9. Solutions
10. Peroxides

Related Therapies and Procedures

1. Therapeutics