pyrromycin

Also Known As:

(1R-(1 alpha,2 beta,4 beta))-2-ethyl-1,2,3,4,6,11- hexahydro-2,5,7,10-tetrahydroxy-6,11-dioxo-4- ((2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo- hexopyranosyl)oxy)-1-naphthacenecarboxylic acid, methyl ester

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Naphthacenes
        Anthracyclines: 9423
        pyrromycin: 4
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Naphthacenes
    - Anthracyclines: 9423
      - pyrromycin: 4
Carbohydrates: 22023
- Glycosides: 2119
  - Aminoglycosides: 5131
    - Anthracyclines: 9423
      - pyrromycin: 4

Related Diseases

1.	Leukemia 03/01/1988 - "The present studies revealed that pyrromycin, a closely related monosaccharide-anthracycline, induced erythroid differentiation in Friend leukemia cells and in the human leukemia cell line K 562. " 07/01/1984 - "The trisaccharide-containing anthracyclines aclacinomycin A (ACM) and marcellomycin (MCM) have been shown by our laboratory to be potent inducers of HL-60 leukemia cell maturation, while the monosaccharide-containing anthracyclines Adriamycin and pyrromycin were inactive and significantly less potent, respectively, as initiators of the differentiation of these malignant cells. "
2.	Acute Erythroblastic Leukemia (Erythroleukemia) 02/01/1991 - "The effect of adriamycin, daunomycin, N,N-dimethyladriamycin, N,N-dimethyldaunomycin, pyrromycin, marcellomycin, and aclacinomycin A on erythroid differentiation and glycoprotein synthesis in Friend erythroleukemia cells, clone F4-6 was investigated. " 07/01/1982 - "Effects of the structural analogues, adriamycin (ADM), daunomycin (DNM), carminomycin (CMM), 4-demethoxydaunomycin (4D-DNM), pyrromycin (PYM), marcellomycin (MCM), and aclacinomycin (ACM) upon total cell RNA synthesis and the appearance of total RNA and poly(A)+-RNA in the cytoplasm of uninduced Friend erythroleukemia cells were investigated. "

Related Drugs and Biologics

1.	Anthracyclines
2.	Monosaccharides
3.	Doxorubicin (Adriamycin)
4.	marcellomycin
5.	Aclarubicin
6.	Daunorubicin (Cerubidine)
7.	Trisaccharides
8.	Messenger RNA (mRNA)
9.	RNA (Ribonucleic Acid)
10.	Glycoproteins (Glycoprotein)