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2-methylthioadenosine

Also Known As:

2-(methylthio)adenosine

Networked: 6 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Chen, Jiefang: 1 article (01/2021)
2.	Dang, Yiping: 1 article (01/2021)
3.	Guo, Xiaoqing: 1 article (01/2021)
4.	He, Hui: 1 article (01/2021)
5.	He, Quanwei: 1 article (01/2021)
6.	Hu, Bo: 1 article (01/2021)
7.	Hu, Yu: 1 article (01/2021)
8.	Jin, Huijuan: 1 article (01/2021)
9.	Li, Yanan: 1 article (01/2021)
10.	Li, Yuanyuan: 1 article (01/2021)

Related Diseases

1.	Tics (Tic) 01/01/2021 - ": 2-MeSAMP: 2-methylthioadenosine 5'-monophosphate; 8-CPT-cAMP: 8-(4-chlorophenylthio)-adenosine-3',5'-cyclic-monophosphate; ABCA1: ATP binding cassette subfamily A member 1; ABCG1: ATP binding cassette subfamily G member 1; ACTB: actin beta; ADPβs: adenosine 5'-(alpha, beta-methylene) diphosphate; ALs: autolysosomes; AMPK: AMP-activated protein kinase; APOA1: apolipoprotein A1; APs: autophagosomes; ATG5: autophagy related 5; ATV: atorvastatin; AVs: autophagic vacuoles; CD: chow diet; CDL: clopidogrel; CQ: chloroquine; DAPI: 4',6-diamidino-2-phenylindole; dbcAMP: dibutyryl-cAMP; DIL-oxLDL: dioctadecyl-3,3,3,3-tetramethylin docarbocyanine-oxLDL; EIF4EBP1/4E-BP1: eukaryotic translation initiation factor 4E binding protein 1; EVG: elastic van gieson; HE: hematoxylin-eosin; HDL: high-density lipoprotein; HFD: high-fat diet; KEGG: Kyoto Encyclopedia of Genes and Genomes; LDL-c: low-density lipoprotein cholesterol; LDs: lipid droplets; MAP1LC3/LC3: microtubule associated protein 1 light chain 3; Masson: masson trichrome; MCPT: maximal carotid plaque thickness; MK2206: MK-2206 2HCL; NBD-cholesterol: 22-(N-[7-nitrobenz-2-oxa-1,3-diazol-4-yl] amino)-23,24-bisnor-5-cholen-3β-ol; OLR1/LOX-1: oxidized low density lipoprotein receptor 1; ORO: oil Red O; ox-LDL: oxidized low-density lipoprotein; SQSTM1/p62: sequestosome 1; TEM: transmission electron microscopy; TIC: ticagrelor; ULK1: unc-51 like autophagy activating kinase 1; VSMCs: vascular smooth muscle cells."
2.	Wounds and Injuries (Trauma) 06/22/2011 - "The administration of 2-methylthioadenosine 5'-diphosphate (2MeSADP), a selective agonist for P2Y₁R, induced marked increases in patterns of glioma migration in both scratch wound and Boyden chamber assays. "
3.	Neuralgia (Stump Neuralgia) 12/01/2017 - "Administration of the P2Y1,12,13 receptor agonist, 2-(methylthio)adenosine 5'-diphosphate trisodium salt hydrate (2-MeSADP), to naïve rats induced neuropathic pain in the tongue, as in lingual nerve crush rats. "
4.	Neoplasms (Cancer) 09/01/2023 - "The analysis revealed that concentration level of 2-methylthioadenosine was decreased, while for inosine, it was increased 24 h after tumor resection in comparison to the preoperative state. "
5.	Hypersensitivity (Allergy) 02/01/2015 - "We found that intrathecal injection of 2-(methylthio)adenosine 5'-diphosphate (2Me-SADP) induced mechanical hypersensitivity and p38 mitogen-activated protein kinase (MAPK) phosphorylation in the spinal cord. "

Related Drugs and Biologics

1.	methylthio-ADP
2.	AMP-Activated Protein Kinases
3.	Class E Scavenger Receptors (Lectin Like Oxidized Low Density Lipoprotein Receptor 1)
4.	p38 Mitogen-Activated Protein Kinases
5.	Apolipoprotein A-I (Apolipoprotein A1)
6.	Salts
7.	Diphosphates (Pyrophosphates)
8.	Peptide Initiation Factors (Initiation Factor)
9.	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)
10.	LDL Cholesterol

Related Therapies and Procedures

1.	Spinal Injections