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IgA-specific serine endopeptidase

extracellular microbial enzymes whose only substrate is human IgA of the IgA1 subclass; cleave the immunoglobulin at a specific internal prolyl-threonyl peptide bond in the heavy chain to yield intact Faba & Fca fragments; consider also EC 3.4.24.13
Also Known As:
IgA protease; IgA1 protease; immunoglobulin A(1) protease; immunoglobulin A1 protease
Networked: 68 relevant articles (2 outcomes, 5 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Murphy, Timothy F: 5 articles (11/2018 - 01/2011)
2. Kirkham, Charmaine: 4 articles (01/2018 - 01/2011)
3. Pettigrew, Melinda M: 3 articles (01/2018 - 12/2015)
4. Tettelin, Hervé: 2 articles (01/2022 - 01/2018)
5. Fan, Junming: 2 articles (02/2018 - 01/2016)
6. Wang, Honglian: 2 articles (02/2018 - 01/2016)
7. Wang, Li: 2 articles (02/2018 - 01/2016)
8. Gallo, Mary C: 2 articles (01/2018 - 12/2017)
9. Kong, Yong: 2 articles (01/2018 - 12/2015)
10. Sethi, Sanjay: 2 articles (12/2015 - 01/2011)

Related Diseases

1. Urethritis
2. IGA Glomerulonephritis (IGA Nephropathy)
3. Infections
4. Chronic Obstructive Pulmonary Disease (COPD)
5. Pneumococcal Infections

Related Drugs and Biologics

1. Transferrin (beta 2 Transferrin)
2. Lactoferrin
3. Iron
4. opacity proteins
5. Immunoglobulin A (IgA)
6. Immunoglobulin G (IgG)
7. Antibodies
8. Peptide Hydrolases (Proteases)
9. Immunoglobulins (Immunoglobulin)
10. Proteins (Proteins, Gene)

Related Therapies and Procedures

1. Therapeutics
2. Critical Care (Surgical Intensive Care)