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tissue-factor-pathway inhibitor 2 (PP5)

glycoprotein containing 20% carbohydrate which moves as a beta(1) globulin on electrophoresis; MW 36,000; TFPI-2 is an important regulator of the extrinsic pathway of blood coagulation; a factor VIIA antagonist; present in placenta, maternal serum in late pregnancy, liver, heart, pancreas, and other tissues; a serine protease inhibitor; GenBank L27624 (human); REfSeq NM_006528 (human), NM_009364 (mouse)
Also Known As:
PP5; MSPI protein; PP5 protein, human; PP5 protein, mouse; Placental protein 5, human; TFPI-2; TFPI2 protein, human; Tfpi2 protein, mouse; matrix-associated serine protease inhibitor; placenta-specific protein 5; placental protein 5; tissue factor pathway inhibitor 2 protein, human; tissue factor pathway inhibitor 2 protein, mouse; tissue factory pathway inhibitor-2
Networked: 294 relevant articles (7 outcomes, 63 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Kisiel, Walter: 11 articles (05/2008 - 01/2002)
2. Ma, Duan: 8 articles (10/2015 - 02/2004)
3. Kobayashi, Hiroshi: 7 articles (09/2022 - 08/2015)
4. Nadir, Yona: 7 articles (01/2020 - 04/2010)
5. Iochmann, Sophie: 6 articles (01/2021 - 07/2003)
6. Reverdiau, Pascale: 6 articles (01/2021 - 07/2003)
7. Honkanen, Richard E: 6 articles (11/2011 - 11/2004)
8. Dinh, Dzung H: 6 articles (06/2007 - 01/2002)
9. Gujrati, Meena: 6 articles (06/2007 - 01/2002)
10. Rao, Jasti S: 6 articles (06/2007 - 01/2002)

Related Diseases

1. Neoplasms (Cancer)
2. Weight Gain
3. Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
4. Pre-Eclampsia (Preeclampsia)
5. Myocardial Ischemia (Ischemic Heart Diseases)

Related Drugs and Biologics

1. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
2. Luteolin
3. NG-Nitroarginine Methyl Ester (L-NAME)
4. Glucose (Dextrose)
5. vitexin
6. Proteins (Proteins, Gene)
7. Matrix Metalloproteinases (MMPs)
8. tissue-factor-pathway inhibitor 2 (PP5)
9. lipoprotein-associated coagulation inhibitor (TFPI)
10. Serine Proteinase Inhibitors (Serine Protease Inhibitors)

Related Therapies and Procedures

1. Therapeutics
2. Filtering Surgery
3. RNAi Therapeutics
4. Intravitreal Injections
5. Microbubbles