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oxyhyponitrite

nitrosating agent; structure given in first source; RN given refers to parent acid

Also Known As:

Angeli's salt; hyponitric acid, disodium salt; sodium trioxodinitrate; hyponitric acid

Networked: 24 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Inorganic Chemicals: 9
- Electrolytes: 16106
  - Ions: 7857
    - Anions: 3501
      - Nitrites: 4928
        oxyhyponitrite: 24
- Nitrogen Compounds: 67
  - Nitrous Acid: 38
    - Nitrites: 4928
      - oxyhyponitrite: 24
Organic Chemicals: 133
- Nitrites: 4928
  - oxyhyponitrite: 24

Experts

1.	Miranda, Katrina M: 7 articles (01/2017 - 05/2002)
2.	Casagrande, Rubia: 4 articles (01/2017 - 08/2013)
3.	Verri, Waldiceu A: 4 articles (01/2017 - 08/2013)
4.	Cunha, Fernando Q: 3 articles (08/2016 - 08/2013)
5.	Cunha, Thiago M: 3 articles (08/2016 - 08/2013)
6.	Wink, David A: 3 articles (12/2005 - 05/2002)
7.	Pinho-Ribeiro, Felipe A: 2 articles (01/2017 - 08/2016)
8.	Staurengo-Ferrari, Larissa: 2 articles (01/2017 - 08/2014)
9.	Alves-Filho, José C: 2 articles (08/2016 - 08/2014)
10.	Longhi-Balbinot, Daniela T: 2 articles (08/2016 - 08/2014)

Related Diseases

1.	Infectious Arthritis (Septic Arthritis) 01/01/2017 - "The nitroxyl donor Angeli's salt ameliorates Staphylococcus aureus-induced septic arthritis in mice."
2.	Pain (Aches) 08/01/2014 - "In the present study, the antinociceptive effect of the nitroxyl (HNO) donor, Angeli's salt (Na2N2O3; AS) was investigated in models of overt pain-like behavior. " 08/25/2016 - "We have recently demonstrated the analgesic effect of the nitroxyl donor, Angeli's salt (AS) in models of inflammatory pain. "
3.	Neoplasms (Cancer) 11/25/2013 - "In the present study Angeli's salt (Na2N2O3) was used as the nitroxyl donor and cytotoxicity of HNO/NO(-) against human lymphocytes and A549 and HT29 cancer cells was examined. "
4.	Heart Failure 01/13/2009 - "Due to its potential applications in new therapies for heart failure, the dissociation of Angeli's salt has recently received increased attention. " 12/01/2020 - "Twenty six male Wistar rats were randomly divided into heart failure group (HF group), Angeli's salt treatment group (HF + AS group) and sham operation group (Sham group). " 01/01/2013 - "Nitroxyl (HNO) has gained interest as a potential treatment of congestive heart failure through the ability of the HNO donor, Angeli's salt (AS), to evoke positive inotropic effects in canine cardiac muscle. " 12/29/2005 - "The NONOate Angeli's salt (Na(2)N(2)O(3)) releases nitroxyl (HNO) under physiological conditions and exhibits unique cardiovascular features (i.e., positive inotropy/lusitropy) that may have relevance for pharmacological treatment of heart failure. " 05/01/2009 - "Nitroxyl (HNO) exhibits many important pharmacological effects, including inhibition of platelet aggregation, and the HNO donor Angeli's salt has been proposed as a potential therapeutic agent in the treatment of many diseases including heart failure and alcoholism. "
5.	Reperfusion Injury 02/01/2016 - "The HNO donor Angeli's salt offers potential haemodynamic advantages over NO or dobutamine in ischaemia-reperfusion injury in the rat heart ex vivo." 09/01/2009 - "Hence, we studied the effect of the classical HNO-donor, Angeli's salt (AS), on a cerebral ischemia/reperfusion injury in a mouse model of experimental stroke and on related in vitro paradigms of neurotoxicity. "

Related Drugs and Biologics

1.	nitroxyl
2.	Peroxynitrous Acid (Peroxynitrite)
3.	S-Nitrosoglutathione
4.	Nitric Oxide Donors
5.	Calcitonin Gene-Related Peptide Receptors (Calcitonin-Gene Related Peptide Receptor)
6.	Reactive Oxygen Species (Oxygen Radicals)
7.	Sodium
8.	Penicillamine (Cuprimine)
9.	Papaverine
10.	Nitroprusside (Sodium Nitroprusside)

Related Therapies and Procedures

1.	Therapeutics