staphylococcal alpha-toxin

04/01/1985 - "[Characteristics of a staphylococcal infection in guinea pigs with delayed hypersensitivity to staphylococcal alpha-toxin]."
02/01/2008 - "Our results demonstrate that IFNs may increase cell resistance to staphylococcal alpha-toxin via the regulation of lipid metabolism and suggest that interferons play a protective role during staphylococcal infections."
10/01/1965 - "The results suggest a possible role of vasoactive staphylococcal alpha-toxin, as well as epinephrine or epinephrine-like factors, in this altered state of resistance to staphylococcal infection."
01/01/2018 - "We further demonstrate that SSHELs covalently modified with a catalytically inactivated staphylococcal alpha toxin variant (HlaH35L), without an adjuvant, resulted in improved protection against Staphylococcus aureus infection in a bacteremia model as compared to vaccination with the antigen alone. "
02/01/1970 - "The effect of the widely employed oral contraceptive steroid, Enovid, on the cytolytic action of the staphylococcal alpha toxin was investigated as an extension of previous studies in which it was shown that steroids were capable of suppressing induced staphylococcal infection in experimental animals. "

01/01/2018 - "We further demonstrate that SSHELs covalently modified with a catalytically inactivated staphylococcal alpha toxin variant (HlaH35L), without an adjuvant, resulted in improved protection against Staphylococcus aureus infection in a bacteremia model as compared to vaccination with the antigen alone. "
01/01/1986 - "Antibody responses to staphylococcal alpha-toxin, cell wall teichoic acid, and cell wall peptidoglycan were measured in 259 serum samples from 74 consecutive patients with Staphylococcus aureus bacteremia. "

09/01/1986 - "The early events in staphylococcal alpha-toxin action on mouse adrenocortical (Y1) tumor cells were studied. "
09/01/1986 - "Early events in the action of staphylococcal alpha-toxin on the plasma membrane of adrenocortical Y1 tumor cells."
01/01/1987 - "Staphylococcal alpha-toxin also stimulated 3-fold the specific binding of a radioactive tumor-promoting phorbol ester (PDBu) to PC12 cells at concentrations similar to those required for the inhibition of [125I]EGF binding. "
01/01/1970 - "The present study indicates that the synthetic estrogenic hormone diethylstilbestrol which is used for acne, estrogen deficiency, cancer, and other disorders, can reduce the cytolytic action of staphylococcal alpha toxin. "
02/01/1994 - "Previous reports concerning the effects of calcium ionophores on rodent thymocytes and the pore-forming proteins perforin and staphylococcal alpha-toxin on murine tumor cells led to the suggestion that simply raising intracellular calcium causes apoptotic cell death. "

09/01/1984 - "Staphylococcal alpha-toxin elicits hypertension in isolated rabbit lungs. "
09/01/1984 - "The conclusion drawn from these studies is that staphylococcal alpha-toxin provokes pulmonary vascular hypertension which is apparently mediated by thromboxane A2 formation, which surpasses the biological effect of the simultaneously formed prostaglandin I2. "

04/01/1963 - "Studies of the Biologic Activity of Purified Staphylococcal Alpha-Toxin: II. The Effect of Alpha-Toxin on Ehrlich Ascites Carcinoma Cells."