carbetocin

Also Known As:

1-deamino-1-monocarba-2-(Tyr(OMe))-oxytocin; Depotocin; dcomot; oxytocin, 1-desamino-1-monocarba-(Tyr(OMe))(2)-; oxytocin, 1-desamino-1-monocarba-(tyrosine(O-methyl))(2)-; 1-Carbaoxytocin, 1-butanoic acid-2-(O-methyl-L-tyrosine)-

Networked: 134 relevant articles (22 outcomes, 36 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Hormones, Hormone Substitutes, and Hormone Antagonists
- Hormones: 80400
  - Peptide Hormones: 1347
    - Pituitary Hormones: 601
      - Posterior Pituitary Hormones: 176
        Oxytocin: 4917
        carbetocin: 134
Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Peptide Hormones: 1347
    - Pituitary Hormones: 601
      - Posterior Pituitary Hormones: 176
        Oxytocin: 4917
        carbetocin: 134

Experts

1.	Widmer, Mariana: 4 articles (12/2022 - 01/2018)
2.	Gülmezoglu, A Metin: 3 articles (06/2022 - 08/2018)
3.	Carvalho, Jose C A: 3 articles (01/2022 - 08/2012)
4.	Coomarasamy, Arri: 3 articles (08/2018 - 09/2014)
5.	Wang, Peng-Hui: 3 articles (01/2018 - 12/2016)
6.	Goudar, Shivaprasad S: 2 articles (12/2022 - 08/2018)
7.	Piaggio, Gilda: 2 articles (12/2022 - 08/2018)
8.	Pujar, Yeshita V: 2 articles (12/2022 - 08/2018)
9.	Rosseland, Leiv Arne: 2 articles (01/2021 - 09/2013)
10.	Hofmeyr, G Justus: 2 articles (08/2018 - 01/2018)

Related Diseases

1.	Postpartum Hemorrhage 06/01/2018 - "Carbetocin is effective in reducing the use of additional uterotonics, reduction in postpartum hemorrhage and transfusion when used during cesarean deliveries. " 07/01/2021 - "Efficacy of carbetocin in the prevention of postpartum hemorrhage: a systematic review and Bayesian meta-analysis of randomized trials." 07/01/2021 - "To evaluate the efficacy of carbetocin for the prevention of postpartum hemorrhage (PPH) and related events after vaginal or cesarean delivery. " 12/01/2016 - "The aim of this retrospective observational study was to determine the efficacy of carbetocin in reducing blood loss and primary postpartum hemorrhage (PPH) in vaginal and cesarean deliveries in a tertiary hospital in Taiwan. " 01/01/2021 - "Side-effects of carbetocin to prevent postpartum hemorrhage: A systematic review and meta-analysis of randomized controlled trials."
2.	Hemorrhage 12/01/2022 - "Carbetocin for the prevention of post-partum hemorrhage after vaginal birth: a real-world application." 06/01/2018 - "Ferring Pharmaceuticals, the World Health Organization, and MSD for Mothers have established a collaboration to develop this heat-stable formulation of carbetocin for the prevention of post-partum hemorrhage in women after vaginal childbirth, with the aim of making the medicine available in the public sector of developing countries that have a high burden of maternal mortality." 09/01/2017 - "Analysis of the cost-effectiveness of carbetocin for the prevention of hemorrhage following cesarean delivery in Ecuador." 02/01/2014 - "QT interval prolongation following carbetocin in prevention of post-cesarean delivery hemorrhage." 07/01/2011 - "[Carbetocin use to prevent obstetric hemorrhage]."
3.	Retained Placenta 10/01/2019 - "Intra-umbilical carbetocin is more effective than intra-umbilical oytocin as a method for management of retained placenta. " 10/01/2019 - "The aim of this study was to compare the efficacy of intra-umbilical vein injection of carbetocin versus oxytocin in the management of retained placenta. " 08/01/2015 - "This study aimed to compare the hemodynamic profile and efficacy of carbetocin versus intra-umbilical oxytocin in the management of retained placenta following vaginal delivery. " 10/01/2019 - "Intra-umbilical carbetocin seems to have more acceptable hemodynamic safety profile when compared to intra-umbilical oxytocin in the management of retained placenta." 10/01/2019 - "Intra-umbilical vein injection of carbetocin versus oxytocin in the management of retained placenta."
4.	Uterine Inertia 01/01/2016 - "Costs of the use of carbetocin in the prevention of uterine atony following delivery of the infant by Caesarean section - retrospective multicenter study." 12/01/2010 - "[Use of carbetocin in prevention of uterine atony during cesarean section. " 11/01/2009 - "Carbetocin is currently indicated for prevention of uterine atony after delivery by caesarean section in spinal or epidural anaesthesia. " 01/01/2016 - "Carbetocin is recommended as prophylaxis of obstetric hemorrhage in patients with risk factors for uterine atony. " 09/01/2013 - "Oxytocin is the first-line treatment for uterine atony, although the effects of the long-acting oxytocin analogue carbetocin are comparable with that of oxytocin. "
5.	Hyperphagia (Overeating) 01/01/2018 - "carbetocin was well tolerated and improved hyperphagia and behavioral symptoms of PWS. " 06/16/2023 - "Carbetocin was well tolerated, and the 3.2-mg dose was associated with clinically meaningful improvements in hyperphagia and anxiousness and distress behaviors in participants with PWS. " 06/16/2023 - "Intranasal Carbetocin Reduces Hyperphagia, Anxiousness, and Distress in Prader-Willi Syndrome: CARE-PWS Phase 3 Trial." 01/01/2018 - "Intranasal carbetocin reduces hyperphagia in individuals with Prader-Willi syndrome." 01/01/2023 - "The only two compounds with evidence of significant effects that were replicated in ≥ 1 additional RCT without any negative RCTs were dasotraline for attention-deficit/hyperactivity disorder, and carbetocin for hyperphagia in Prader-Willi syndrome. "

Related Drugs and Biologics

1.	Oxytocin (Pitocin)
2.	syntometrine
3.	Ergonovine (Ergometrine)
4.	Oxytocics
5.	Misoprostol (Cytotec)
6.	Tranexamic Acid (AMCA)
7.	Hemoglobins (Hemoglobin)
8.	denaverine
9.	Carboprost
10.	Methylergonovine (Methergine)

Related Therapies and Procedures

1.	Cesarean Section (Caesarean Section)
2.	Uterine Myomectomy
3.	General Anesthesia
4.	Blood Transfusion (Blood Transfusions)
5.	Spinal Anesthesia