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MME

Also Known As:

1,2,3,4,9,9-hexachloro-1,4,4a,5,8,8a-hexahydro-6- methyl-6,7-epoxy-1,4-methanonaphthalene; 3,6-Methanonaphth(2,3-b)oxirene, 3,4,5,6,8,8-hexachloro-1a,2,2a,3,6,6a,7,7a-octahydro-1a-methyl-, (1aalpha,2abeta,3alpha,6alpha,6abeta,7aalpha)-

Networked: 107 relevant articles (3 outcomes, 22 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 58
- Hydrocarbons: 412
  - Halogenated Hydrocarbons: 31
    - Chlorinated Hydrocarbons: 157
      - Endrin: 44
        MME: 107

Experts

1.	Mutti, Luciano: 9 articles (12/2013 - 11/2002)
2.	Moro, Laura: 5 articles (12/2013 - 01/2010)
3.	Ranzato, Elia: 4 articles (01/2014 - 01/2011)
4.	Burlando, Bruno: 4 articles (01/2014 - 01/2011)
5.	Manente, Arcangela Gabriella: 4 articles (02/2013 - 01/2010)
6.	Pinton, Giulia: 4 articles (02/2013 - 01/2010)
7.	Martinotti, Simona: 3 articles (01/2014 - 12/2011)
8.	Shi, Hai: 3 articles (01/2012 - 02/2006)
9.	Mei, Qiao: 3 articles (01/2012 - 02/2006)
10.	Porta, Camillo: 3 articles (10/2007 - 11/2002)

Related Diseases

1.	Neoplasms (Cancer) 02/01/2012 - "This study demonstrates for the first time in a metastatic animal model that MME, as a monotherapy or in combination with oncolytic virus, does not increase tumor invasiveness. " 11/01/2006 - "In the present study, we evaluated anti tumor activities of LNT and MME in tumor-bearing mice (B10.D2 mice implanted with S908D2 tumor cells) and examined the mechanism of immunopotentiation of these substances. " 12/01/2013 - "The EGCG-dependent negative modulation of mitochondrial energy metabolism, selective for cancer cells, gives an important input for the development of novel pharmacological strategies for MMe. " 01/01/2013 - "Exon sequencing of 13 HH pathway genes was also performed in cell lines and human MMe tumors. " 01/01/2011 - "Alterations in expression levels of genes, such as LOX, ATP5L, GALNT3, and MME revealed by large-scale sequencing were confirmed between cell lines as well as in tumor specimens with different ERBB2 backgrounds. "
2.	Constipation 12/01/2011 - "The purpose of this study was to determine the safety and efficacy of routine milk and molasses enemas (MME) compared with sodium phosphate enemas for the treatment of constipation in the pediatric emergency department (ED). " 12/01/2011 - "Medical records of patients who presented to the ED and received either MME or sodium phosphate enema for constipation between November 1, 2007, and November 1, 2008, were identified and reviewed for data collection. "
3.	Melanoma (Melanoma, Malignant) 02/01/2014 - "T-cell infiltration into the metastatic melanoma microenvironment (MME) correlates with improved patient survival. " 05/01/2000 - "These results show that placing MME gene directly into B16-BL6 melanoma cells is an effective approach to suppress primary tumor growth in vivo because it halts angiogenesis. " 07/01/2015 - "A single melanocytic lesion of the esophagus should be differentiated from a primary malignant melanoma of the esophagus (PMME) or an esophageal metastatic melanoma (MME). " 09/01/2001 - "We previously demonstrated that gene replacement of mouse macrophage metalloelastase (MME) into murine melanoma cells that grow rapidly and are MME deficient suppresses the primary tumor growth in vivo by halting angiogenesis. " 05/01/2000 - "To clarify whether tumor cells that consistently generate MME can suppress angiogenesis and, therefore, inhibit the growth of primary tumors in vivo, we transfected a cDNA coding for MME into murine B16-BL6 melanoma cells that grow rapidly and are MME deficient. "
4.	Mesothelioma 07/01/2005 - "To foster discussion among investigators working in this field, and to exchange different viewpoints concerning the newest advances in MMe pathogenesis and treatment, the VII International Mesothelioma Interest Group (IMIG) meeting was held in Brescia (Italy) between 24 and 26 June 2004 in cooperation with the Italian Group for the Study and Therapy of MMe (GIMe). " 01/01/2013 - "The extent to which mutations of the HH pathway genes are involved in the pathogenesis of malignant mesothelioma (MMe) is unknown. " 11/01/2012 - "Malignant mesothelioma (MMe) is a highly aggressive, lethal tumour requiring the development of more effective therapies. " 05/01/2012 - "This article evaluates the application of CTC as a potentially useful diagnostic and prognostic test in malignant pleural mesothelioma (MMe). " 01/01/2012 - "PI3K/AKT signalling pathway is aberrantly active and plays a critical role for cell cycle progression of human malignant pleural mesothelioma (MMe) cells. "
5.	Mastocytoma 05/01/1992 - "In the present study, we demonstrate that TGF-beta inhibits basal and TNF-enhanced binding of murine P815 mastocytoma cells to murine microvascular endothelium (MME). " 09/01/1991 - "We have previously demonstrated that the exposure of mouse microvascular endothelium (MME) to tumor necrosis factor-alpha (TNF) led to the increased binding of mouse mastocytoma cells (P815) to endothelial monolayers (Bereta et al., in press). " 04/01/1993 - "Studies on the inhibition of cell binding by monoclonal antibodies against mouse VCAM-1 and mouse VLA-4 indicated that VCAM-1 plays a dominant role in mediating the adherence of a variety of cell types, including murine splenocytes and thymocytes, P815 mastocytoma cells, PT 18 mast/basophil cells, human Molt-4 cells, and human eosinophils, to cytokine-activated MME."

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5.	Neprilysin (Neutral Endopeptidase)
6.	Matrix Metalloproteinase 12
7.	Angiostatins
8.	Complementary DNA (cDNA)
9.	Retinaldehyde (Retinal)
10.	Amyloid (Amyloid Fibrils)

Related Therapies and Procedures

1.	Enema (Enemas)
2.	Heterologous Transplantation (Xenotransplantation)
3.	Investigational Therapies (Experimental Therapy)
4.	Distraction Osteogenesis
5.	Bone Marrow Transplantation (Transplantation, Bone Marrow)