gamma- hydroxy- gamma- ethyl- gamma- phenylbutyramide (HEPB)

Also Known As:

HEPB; 4-HPHM; 4-hydroxy,4-phenylcaproamide; 4-hydroxy-4-phenylcaproamide; 4-hydroxy-4-phenylhexanamide; HPhCA; gamma-hydroxy, gamma-ethyl, gamma-phenyl-butyramide; Benzenebutanamide, gamma-ethyl-gamma-hydroxy-

Networked: 339 relevant articles (15 outcomes, 47 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Carbocyclic Acids
    - Phenylbutyrates
      - gamma-hydroxy-gamma-ethyl-gamma-phenylbutyramide: 339

Experts

1.	Centers for Disease Control and Prevention (CDC): 17 articles (08/2014 - 03/2003)
2.	Yankey, David: 12 articles (10/2021 - 08/2014)
3.	Nelson, Noele P: 11 articles (04/2022 - 04/2014)
4.	Elam-Evans, Laurie D: 11 articles (10/2021 - 08/2014)
5.	Murphy, Trudy V: 11 articles (05/2016 - 09/2011)
6.	Singleton, James A: 10 articles (10/2021 - 08/2014)
7.	Tohme, Rania A: 9 articles (01/2022 - 01/2017)
8.	Hill, Holly A: 8 articles (10/2021 - 08/2015)
9.	Schillie, Sarah: 6 articles (01/2022 - 12/2013)
10.	Woodring, Joseph: 6 articles (01/2021 - 12/2017)

Related Diseases

1.	Hepatitis B 09/16/2011 - "To improve protection against hepatitis B among high-risk adults, healthcare providers should offer hepatitis B vaccination to persons at high risk and those who seek vaccination to protect themselves and facilitate timely completion of the three (3) dose HepB series." 01/01/2023 - "Yet, hepatitis B birth dose (HepB-BD) vaccination, which is effective in preventing mother-to-child transmission of hepatitis B, remains low in sub-Saharan Africa. " 08/28/2022 - "A group of 100 children with a history of primary hepatitis B immunization were included in this study to evaluate the efficacy of HepB. " 01/01/2015 - "Revaccination on adult HepB non-responders increased the immune response to HepB and may confer further protection against hepatitis B virus infection. " 06/01/2009 - "It have remarkably improved the coverage of HepB and knowledge on Hepatitis B prevention, interrupted mother-to-infant transmission effectively as well as. "
2.	Infections 01/01/2023 - "Whilst HepB LiveTest holds promise for reducing HBV prevalence in underserved populations, caution is warranted when implementing the model in older populations, particularly in regions with low incidence of HBV infection." 01/01/2023 - "In this study, we aimed to externally assess the clinical validity and portability of HepB LiveTest in predicting HBV infection among independent patient cohorts from Nigeria and Australia. " 11/30/2022 - "This phase 3, multicenter, single-group, open-label challenge study (NCT04490499; EudraCT: 2020-000126-26) evaluated immune memory against HepB infection in children who had received DTaP5-IPV-HepB-Hib at 2, 4, and 11-12 months of age, or at 2, 3, 4, and 12 months of age. " 10/01/2021 - "This study aimed to systematically evaluate the implementation and influencing factors of PVST to further reduce HBV infection risk in infants and improve the protective effect of HepB to the greatest extent. " 09/01/2012 - "A total of 11 590 adults who were 18 - 49 years old, never received HepB vaccination, without HBV infection history, HBs-Ag negative, and had been living at 3 towns of Zhangqiu county in Shandong province Ji'nan city for more than half a year, were selected in the study in July, 2009. "
3.	Poliomyelitis (Polio) 02/01/2018 - "Efficacy of Arsenicum album 30cH in preventing febrile episodes following DPT-HepB-Polio vaccination - a randomized, double-blind, placebo-controlled clinical trial." 02/01/2018 - "In the community medicine out-patient of Mahesh Bhattacharyya Homoeopathic Medical College and Hospital, West Bengal, India, between August 2014 and January 2017, a double-blind, randomized, placebo-controlled trial was conducted on 120 children (verum: 60, placebo: 60) who presented for the 2nd and 3rd dose of DPT-HepB-Polio vaccination and reported febrile episodes following the 1st dose. " 12/31/2022 - "Before the first dose (p = 0.178) and at age 24 months (p = 0.987), no significant differences existed in HepB surface antibody (HBsAb) titers between the six polio immunization program groups). " 06/11/2021 - "Immunisation coverage ranged from 82% [81-84] for the third dose of polio to 97.4% [96.7-98.2] for the first dose of DTP-HepB-Hib, while full immunisation coverage was 68% [66-71] in 2014. " 03/01/2021 - "Among the enrolled 10 033 children, the vaccination rate was 54.1% for BCG, 84.5% for complete HepB vaccination, 54.5% for complete polio vaccination, 51.3% for MCV, and 59.5% for complete DTP vaccination. "
4.	Chronic Hepatitis B 01/01/2016 - "The Tfh responses in healthy control (HC) subjects, chronic hepatitis B (HepB) patients, and HBV-related HCC patients were examined. " 01/01/2023 - "While chronic hepatitis B is incurable, it can be prevented by the safe and effective hepatitis B vaccine (HepB). " 07/20/2023 - "[Ten-year changes in clinical characteristics and antiviral treatment patterns of chronic hepatitis B in China: a CR-HepB-based real-world study]." 12/01/2013 - "Performance evaluation of the HepB Typer-Entecavir kit for detection of entecavir resistance mutations in chronic hepatitis B." 09/03/2014 - "Hepatitis B vaccination in the Philippines was introduced in 1992 to reduce the high burden of chronic hepatitis B virus (HBV) infection in the population; in 2007, a birth dose (HepB-BD) was introduced to decrease perinatal HBV transmission. "
5.	Hepatocellular Carcinoma (Hepatoma) 03/01/2019 - "Hepatitis B vaccine (HepB), which has been available since 1982, provides lifelong protection against hepatitis B virus (HBV) infection and the associated 20%-30% increased lifetime risk for developing cirrhosis or hepatocellular carcinoma among >95% of vaccine recipients (1). "

Related Drugs and Biologics

1.	Hepatitis B Vaccines (Hepatitis B Vaccine)
2.	Vaccines
3.	aluminum sulfate (alum)
4.	Combined Vaccines
5.	Conjugate Vaccines
6.	Antigens
7.	Diphtheria-Tetanus-acellular Pertussis Vaccines (Tripedia)
8.	Tetanus Toxoid (Vaccine, Tetanus)
9.	Polysaccharides (Glycans)
10.	Hepatitis B Surface Antigens (HBsAg)

Related Therapies and Procedures

1.	Renal Dialysis (Hemodialysis)
2.	Stents
3.	Drug-Eluting Stents
4.	Liver Transplantation
5.	Injections