deamido- thyrotropin-releasing hormone

Also Known As:

thyrotropin-releasing hormone, deamido-; TRH, deamido-; TRH-OH; deamido-TRH; pGlu-His-Pro; pyroglutamyl-histidyl-proline; 1-(N- (5-oxo-L-prolyl)-L-histidyl)-L-proline

Networked: 2 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrrolidines: 115
    - Pyrrolidinones: 162
      - Pyrrolidonecarboxylic Acid: 255
        deamido- thyrotropin-releasing hormone: 2
Amino Acids, Peptides, and Proteins: 1
Hormones, Hormone Substitutes, and Hormone Antagonists
- Hormones: 80400
  - Peptide Hormones: 1347
    - Hypothalamic Hormones: 68
      - Pituitary Hormone-Releasing Hormones: 39
        Thyrotropin-Releasing Hormone: 1449
        deamido- thyrotropin-releasing hormone: 2

Related Diseases

1.	Hyperthyroidism 07/01/1979 - "Despite the fact that TRH degradation was significantly greater than TRH-OH degradation in both normal and hyperthyroid serum, no formation of TRH-OH (less than 3.1 ng/incubation tube) from TRH was detected. " 07/01/1979 - "Formation of TRH-OH from TRH was also not noted when normal or hyperthyroid serum was incubated with TRH at substrate concentrations of 62.5 microgram/ml serum. " 07/01/1979 - "During incubations with serum from patients with hyperthyroidism, 42.7 +/- 2.6 ng TRH were degraded compared to only 19.6 +/- 2.0 ng TRH-OH (P less than 0.001). "
2.	Thyroid Diseases (Thyroid Disease) 08/01/1980 - "Using a specific radioimmunoassay (RIA) for deamido TRH (TRH-OH), TRH-OH immunoreactivity (IR) was detected in the urine of 54% of a group of normal subjects and patients with thyroid disease. "

Related Drugs and Biologics

1.	deamido- thyrotropin-releasing hormone