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crotalase

serine protease from venom of eastern diamondback rattlesnake, Crotalus adamanteus

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Peptide Hydrolases: 23957
      - Serine Proteases: 3726
        Serine Endopeptidases: 11
        crotalase: 2
      - Endopeptidases: 633
        Serine Endopeptidases: 11
        crotalase: 2

Related Diseases

1.	Stroke (Strokes) 01/01/1997 - "Ancrod and batroxobin have been investigated in patients with stroke, deep-vein thrombosis, myocardial infarction, peripheral arterial thrombosis, priapism, and sickle-cell crisis; crotalase has not been administered to humans. "
2.	Venous Thrombosis (Deep-Vein Thrombosis) 01/01/1997 - "Ancrod and batroxobin have been investigated in patients with stroke, deep-vein thrombosis, myocardial infarction, peripheral arterial thrombosis, priapism, and sickle-cell crisis; crotalase has not been administered to humans. "
3.	Thrombosis (Thrombus) 01/01/1997 - "Ancrod and batroxobin have been investigated in patients with stroke, deep-vein thrombosis, myocardial infarction, peripheral arterial thrombosis, priapism, and sickle-cell crisis; crotalase has not been administered to humans. "
4.	Priapism 01/01/1997 - "Ancrod and batroxobin have been investigated in patients with stroke, deep-vein thrombosis, myocardial infarction, peripheral arterial thrombosis, priapism, and sickle-cell crisis; crotalase has not been administered to humans. "
5.	Neoplasms (Cancer) 10/01/1986 - "By contrast, mice that received the B16 melanoma cells pretreated with crotalase had an average tumor mass of only 2 mg/mouse.(ABSTRACT TRUNCATED AT 250 WORDS)" 10/01/1986 - "We have used crotalase, a highly purified defibrinogenating serine proteinase from eastern diamondback rattlesnake venom and a fibrinolytic enzyme from southern copperhead venom to modulate selectively the tumor microenvironment in order to evaluate the role of fibrin(ogen) in tumor growth and dissemination. "

Related Drugs and Biologics

1.	Serine Proteases (Serine Protease)
2.	Venoms
3.	Batroxobin
4.	Fibrin
5.	Enzymes
6.	Ancrod (Arvin)
7.	estropipate (Ogen)