biliverdin reductase

01/01/2019 - "Loss of biliverdin reductase-A favors Tau hyper-phosphorylation in Alzheimer's disease."
10/01/2018 - "Biliverdin reductase-A impairment links brain insulin resistance with increased Aβ production in an animal model of aging: Implications for Alzheimer disease."
02/01/2016 - "Impairment of biliverdin reductase-A promotes brain insulin resistance in Alzheimer disease: A new paradigm."
01/01/2011 - "Oxidative and nitrosative modifications of biliverdin reductase-A in the brain of subjects with Alzheimer's disease and amnestic mild cognitive impairment."
04/01/2019 - "Biliverdin Reductase-A Mediates the Beneficial Effects of Intranasal Insulin in Alzheimer Disease."

11/01/2007 - "Heme-oxygenase-1-induced protection against hypoxia/reoxygenation is dependent on biliverdin reductase and its interaction with PI3K/Akt pathway."
02/01/2008 - "In conclusion, biliverdin reductase mediates hypoxia-induced EMT through a PI3K/Akt-dependent pathway."
02/01/2008 - "We investigated this potential role of biliverdin reductase in hypoxia-induced renal tubular EMT. "
11/01/2013 - "Biliverdin reductase plays a crucial role in hypoxia-induced chemoresistance in human glioblastoma."
01/01/2016 - "Hypoxia inhibits pulmonary artery endothelial cell apoptosis via the e-selectin/biliverdin reductase pathway."

03/01/2012 - "Concentrations in excess of 300 μM corresponded to dose dependent loss of cell viability which was associated with enhanced production of H(2)O(2) concomitant to elevation of gene expression for diverse antioxidant enzymes; biliverdin reductase, arsenite inducible RNA associated protein, dithiolethione-inducible gene-1 (DIG-1) and thioredoxin reductase 1. Moreover, Mn initiated significant reduction of gene expression of mitochondrial glutaryl-coenzyme A dehydrogenase (GCDH), an enzyme involved with glutaric acidemia, oxidative stress, lipid peroxidation and striatal degeneration observed in association with severe dystonic-dyskinetic movement disorder. "

01/01/2018 - "Human biliverdin reductase regulates the molecular mechanism underlying cancer development."
01/01/2015 - "Biliverdin reductase: a target for cancer therapy?"
10/01/1999 - "tissue sections were used for immunostaining of biliverdin reductase, pooled isolated tumors and surrounding tissue that did not contain visible tumor were used for Northern blot analysis of mRNA and Western blot analysis of protein. "
01/01/2020 - "Among the significantly up-regulated proteins in the lymph from metastatic tumor-bearing animals were proteins that identified in exosomes include heat shock protein, enolase 1 alpha, S100, and biliverdin reductase B. "
01/01/2007 - "Among a number of signals that were detected as significantly different in the protein profiling analysis, we identified for the first time ferritin light subunit (FLS) and adenylate kinase 3 alpha-like 1 (AK3), showing decreased expressions in hepatic tumor, as well as biliverdin reductase B (BVRB) that was upregulated in HCC. "

01/01/2021 - "Induction of cell apoptosis by biliverdin reductase inhibitor in MCF-7 and MDA-MB-468 breast cancer cell lines: Experimental and in silico studies."
10/05/2016 - "Human biliverdin reductase promotes EMT through the ERK1/2 signal pathway in breast cancer."
01/01/2018 - "Human biliverdin reductase (hBVR), is an enzyme, that converts biliverdin to bilirubin, and has been implicated in epithelial-mesenchymal transition (EMT) in breast cancer. "