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arginyltransferase

Also Known As:

Arg-tRNA protein transferase; Ate1p (protein); arginine aminoacyl-tRNA protein transferase; arginyl-tRNA protein transferase

Networked: 10 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Transferases: 6589
    - Acyltransferases: 374
      - Aminoacyltransferases
        arginyltransferase: 10

Experts

1.	Kashina, Anna: 2 articles (01/2022 - 10/2013)
2.	Gupta, Ankit: 2 articles (06/2020 - 01/2020)
3.	Gupta, Ishita: 2 articles (06/2020 - 01/2020)
4.	Khan, Sameena: 2 articles (06/2020 - 01/2020)
5.	Rana, Santanu: 2 articles (06/2020 - 01/2020)
6.	Sarkar, Ashish: 2 articles (06/2020 - 01/2020)
7.	Sarkar, Sagartirtha: 2 articles (06/2020 - 01/2020)
8.	Singh, Kanika: 2 articles (06/2020 - 01/2020)
9.	Avitan-Hersh, Emily: 1 article (01/2022)
10.	Brown, Kevin: 1 article (01/2022)

Related Diseases

1.	Breast Neoplasms (Breast Cancer) 12/19/2014 - "In this study, we report that inhibition of arginyltransferase 1 (ATE1), an enzyme mediating post-transcriptional protein arginylation, is sufficient to increase MRTF-A activity in MCF-7 human breast carcinoma cells independently of external growth factor stimuli. "
2.	Neoplasms (Cancer) 01/01/2021 - "Arginyltransferase (ATE1) plays critical roles in many biological functions including cardiovascular development, angiogenesis, adipogenesis, muscle contraction, and metastasis of cancer. " 01/01/2016 - "Arginyltransferase suppresses cell tumorigenic potential and inversely correlates with metastases in human cancers." 11/17/2022 - "Protein arginylation mediated by arginyltransferase Ate1 is a posttranslational modification of emerging importance implicated in the regulation of mammalian embryogenesis, the cardiovascular system, tissue morphogenesis, cell migration, neurodegeneration, cancer, and aging. " 01/01/2019 - "Arginyltransferase 1 (Ate1) is the enzyme mediating post-translational protein arginylation, which has recently been identified as a master regulator affecting many cancer-relevant pathways including stress response, cell cycle checkpoints, and cell migration/adhesion. "
3.	Neoplasm Metastasis (Metastasis) 01/01/2021 - "Arginyltransferase (ATE1) plays critical roles in many biological functions including cardiovascular development, angiogenesis, adipogenesis, muscle contraction, and metastasis of cancer. " 01/01/2016 - "Arginyltransferase suppresses cell tumorigenic potential and inversely correlates with metastases in human cancers." 01/01/2019 - "Reduced Arginyltransferase 1 is a driver and a potential prognostic indicator of prostate cancer metastasis."
4.	Cardiomegaly (Heart Hypertrophy) 06/25/2020 - "Author Correction: Arginyltransferase knockdown attenuates cardiac hypertrophy and fibrosis through TAK1-JNK1/2 pathway." 01/01/2020 - "Arginyltransferase knockdown attenuates cardiac hypertrophy and fibrosis through TAK1-JNK1/2 pathway."
5.	Fibrosis (Cirrhosis) 06/25/2020 - "Author Correction: Arginyltransferase knockdown attenuates cardiac hypertrophy and fibrosis through TAK1-JNK1/2 pathway." 01/01/2020 - "Arginyltransferase knockdown attenuates cardiac hypertrophy and fibrosis through TAK1-JNK1/2 pathway."

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Enzymes
3.	Intercellular Signaling Peptides and Proteins (Growth Factors)
4.	Proteasome Inhibitors
5.	Caspase 3 (Caspase-3)
6.	Lysosomal-Associated Membrane Protein 1
7.	Ubiquitin
8.	Reactive Oxygen Species (Oxygen Radicals)
9.	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)
10.	Phosphotransferases (Kinase)