amidase

01/01/1982 - "The significance of measurements of lipid peroxide and a newly-discovered amidase in inflammation."
08/21/2015 - "A Potent Systemically Active N-Acylethanolamine Acid Amidase Inhibitor that Suppresses Inflammation and Human Macrophage Activation."
11/01/2001 - "4. Pre-treatment of mice with the amidase inhibitor phenylmethyl sulphonil fluoride (PMSF, 30 mg kg(-1), i.p.) did not modify the inhibitory effect of PEA, either in control or in mice with inflammation. "
01/01/2015 - "Pharmacological blockade of N-acylethanolamine acid amidase (NAAA) activity is an available approach for inflammation and pain control through restoring the ability of endogenous PEA. "
11/01/2011 - "To investigate the effect of Angelicae Pubescentis Radix (APR) on the activity of endocannabinoid hydrolase and N-acylethanolamine-hydrolyzing acid amidase (NAAA), and to demonstrate the mechanism of anti-inflammatory effect of APR by in vitro lipopolysaccharide (LPS)-induced inflammation model. "

03/01/2013 - "Antinociceptive effects of the N-acylethanolamine acid amidase inhibitor ARN077 in rodent pain models."
01/01/2015 - "Pharmacological blockade of N-acylethanolamine acid amidase (NAAA) activity is an available approach for inflammation and pain control through restoring the ability of endogenous PEA. "
12/11/2014 - "N-(2-Oxo-3-oxetanyl)carbamic acid esters have recently been reported to be noncompetitive inhibitors of the N-acylethanolamine acid amidase (NAAA) potentially useful for the treatment of pain and inflammation. "

02/01/2010 - "In Staphylococcus aureus wild-type, externally applied repeats (R(1,2)) or endogenously expressed amidase were localized exclusively at the cross-wall region, while in Delta tagO mutant that lacks WTA binding was evenly distributed on the cell surface, which explains the increased fragility and autolysis susceptibility of the mutant. "
09/01/2007 - "pneumoniae death at stationary phase is unusual in bacteria and has been conventionally attributed to autolysis by the LytA amidase. "
12/01/1988 - "Stable autolysis-deficient (Lyt-) mutants and their isogenic Lyt+ parents were used in experiments designed to test possible physiological functions of the amidase. "
10/01/2006 - "Biochemical studies indicated that an N-acetylmuramyl-l-alanine amidase is responsible for cell wall breakdown during autolysis. "
06/01/1996 - "This study examined whether differences in autolysis are caused by differences in expression of the major amidase, LytA, or the structure of its peptidoglycan substrate. "

08/04/1982 - "Enzyme-linked immunosorbent assay (ELISA) of acylase in serum of patients with viral hepatitis."
01/01/1979 - "The same chromatographic method was also applied to isolate form 2 of the serum acylase from patients with viral hepatitis and guinea pig placenta."
01/01/1976 - "Activity of Coiactivated acylase in the serum was investigated in 120 children aged 3 months to 15 years, divided into five age groups, suffering from viral hepatitis (VH). "
02/01/1974 - "[Simplified method of determination of blood acylase activity as a new test for preclinical diagnosis of viral hepatitis]."
01/01/1982 - "A genetic study of serum levels of cobalt-activated acylase among susceptible, resistant and semiresistant strains of mice with experimental viral hepatitis."

01/01/1983 - "In lung tissue adjacent to adenocarcinoma, some deviations of acylase properties were observed, similar to that found in tumor, indicating that biochemical changes may be present also in tissues unaffected by the neoplastic growth by the histopathological criteria."
07/27/2012 - "Human nitrilase-like protein 2 (hNit2) is a putative tumor suppressor, recently identified as ω-amidase. "
09/15/1989 - "Using asialofetuin as an acceptor we found, in tumor tissues of 9 out of 10 patients, an increased sialyltransferase activity towards the N-linked chains as determined upon peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase (PNGase) treatment. "
01/01/1980 - "In all cancer tissues the activity of cobalt-activated acylase was markedly increased as compared with the normal tissue. "
01/01/2013 - "The expression of acid ceramidase (AC) - a cysteine amidase that hydrolyses the proapoptotic lipid ceramide - is abnormally high in several human tumors, which is suggestive of a role in chemoresistance. "