alpha-monofluoromethyldopa

structure given in third source; RN given refers to (DL)-isomer

Also Known As:

2-(fluoromethyl)-3-(3,4-dihydroxyphenyl)alanine; MFMD; RMI 71963; alpha-(fluoromethyl)-3-hydroxy-L-tyrosine; alpha-fluoromethyldopa; alpha-monofluoromethyldopa, (L)-isomer; monofluoromethyl-dopa; DL-Tyrosine, alpha-(fluoromethyl)-3-hydroxy-

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Boeren, Evi: 1 article (01/2021)
2.	Faes, Ellen: 1 article (01/2021)
3.	Jacquemyn, Yves: 1 article (01/2021)
4.	Mannaerts, Dominique: 1 article (01/2021)
5.	Ratajczak, Jessica: 1 article (01/2021)
6.	Van Craenenbroeck, Amaryllis H: 1 article (01/2021)
7.	Van Craenenbroeck, Emeline M: 1 article (01/2021)
8.	Witvrouwen, Isabel: 1 article (01/2021)
9.	Abecasis, Goncalo: 1 article (11/2020)
10.	Bergin, Ingrid L: 1 article (11/2020)

Related Diseases

1.	Inflammation (Inflammations) 01/01/2020 - "MFMD did not enhance the effects of exercise on any measures of muscle strength, gait speed, dynamic balance, reaction time, or blood lipids, and there was no effect of either intervention on blood pressure, markers of inflammation, or cartilage turnover. " 01/01/2021 - "Circulating microRNA levels (RT-qPCR), OS and systemic inflammation were assessed in plasma samples (PE 29.5 vs HP 25.8 weeks) and related to extensive in vivo vascular function (flow-mediated dilatation (FMD), modified FMD (mFMD), carotid-femoral pulse wave velocity (CF-PWV), heart rate corrected augmentation index (AIx75) and reactive hyperemia index (RHI)). "
2.	Hyperemia 01/01/2021 - "Circulating microRNA levels (RT-qPCR), OS and systemic inflammation were assessed in plasma samples (PE 29.5 vs HP 25.8 weeks) and related to extensive in vivo vascular function (flow-mediated dilatation (FMD), modified FMD (mFMD), carotid-femoral pulse wave velocity (CF-PWV), heart rate corrected augmentation index (AIx75) and reactive hyperemia index (RHI)). "
3.	Fibromuscular Dysplasia 11/01/2020 - "Monogenic forms of multifocal fibromuscular dysplasia (mFMD) have not been previously defined. "
4.	Carcinoid Tumor (Carcinoid) 11/01/2000 - "To assess the feasibility of targeting these high AAAD levels for chemotherapy, AAAD inhibitors carbidopa (alpha-methyl-dopahydrazine), alpha-monofluoromethyldopa (MFMD), and 3-hydroxybenzylhydrazine (NSD-1015) were incubated (72 h) with NCI-H727 human lung carcinoid cells. "
5.	Aneurysm (Aneurysms) 11/01/2020 - "Approach and Results: We studied 4 independent probands with the COL5A1 pathogenic variant c.1540G>A, p.(Gly514Ser) who presented with arterial aneurysms, dissections, tortuosity, and mFMD affecting multiple arteries. "

Related Drugs and Biologics

1.	alpha-monofluoromethyldopa
2.	Lipids
3.	Carbidopa (Lodosyn)
4.	Circulating MicroRNA
5.	3-hydroxybenzylhydrazine

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)