melanin-concentrating hormone (melanin concentrating hormone)

03/01/2016 - "Melanin-concentrating hormone (MCH) is implicated in the control of food intake, body weight regulation and energy homeostasis. "
01/01/2014 - "Melanin-concentrating hormone (MCH) has been reported to be involved in a variety of behaviors that include feeding, body-weight regulation, anxiety, sleep, and reward behavior. "
01/11/2006 - "To test this possibility for body weight, mice with selective loss of melanin concentrating hormone (MCH) neurons were generated. "
06/01/2005 - "The importance of the melanin-concentrating hormone (MCH) system for regulation of energy homeostasis and body weight has been demonstrated in rodents. "
10/01/2002 - "Acute and chronic administration of melanin-concentrating hormone enhances food intake and body weight in Wistar and Sprague-Dawley rats."

02/23/2022 - "Crosstalk between Melanin Concentrating Hormone and Endocrine Factors: Implications for Obesity."
01/01/2013 - "The potential role for the melanin-concentrating hormone (MCH) signaling pathway in the treatment of obesity is being explored by many. "
06/01/2011 - "The appetite stimulating effects of melanin-concentrating hormone (MCH) continues to be of high interest, and there is substantial support to investigate the use of MCH 1-receptor antagonists for the treatment of obesity. "
09/15/2010 - "Melanin concentrating hormone (MCH) is an important mediator of energy homeostasis and plays role in several disorders such as obesity, stress, depression and anxiety. "
01/01/2010 - "Mechanism of the anti-obesity effects induced by a novel melanin-concentrating hormone 1-receptor antagonist in mice."

08/01/2008 - "Antagonism of central melanin-concentrating hormone 1 receptor alleviates steatohepatitis in mice."
08/01/2008 - "Blockade of brain melanin-concentrating hormone 1 receptor (MCH1R) significantly ameliorates fatty liver as well as obesity. "
10/01/2016 - "κOR colocalizes with melanin concentrating hormone receptor 1 (MCH-R1) in the LHA, and genetic disruption of κOR reduced melanin concentrating hormone-induced liver steatosis. "

12/01/2020 - "We demonstrated in the previous study that Lhx6+ ZI neurons are activated during paradoxical sleep (PS) hypersomnia which was induced by 48-hour PS deprivation, implying their roles in the control of PS like melanin-concentrating hormone (MCH) cells. "
12/01/2020 - "Furthermore, they indicate for the first time that Lhx6+ neurons in the zona incerta, like melanin-concentrating hormone cells in the lateral hypothalamic area, are activated during paradoxical sleep hypersomnia but not during waking. "
12/01/2020 - "Melanin-concentrating hormone neurons in the lateral hypothalamic area and Lhx6+ cells in the zona incerta constituted 5.7 ± 1.5% and 8.8 ± 2.3% of all mCherry+ cells and 20.6 ± 4.8% and 24.6 ± 5.9% of all cFos+ neurons in two periods of paradoxical sleep hypersomnia in animals. "
09/01/2011 - "Melanin concentrating hormone in central hypersomnia."
11/10/2007 - "We have recently shown that 58% of a hypothalamic neuronal population, the melanin-concentrating hormone (MCH) neurons, are activated after a PS hypersomnia and that MCH, when injected intracerebroventricularly, induces a dose-dependent increase in PS. "

07/01/2006 - "The aim of this study was to validate melanin-concentrating hormone (MCH)-1 receptor antagonism as a potential treatment of mood disorders. "
09/01/2009 - "The role of melanin-concentrating hormone in energy homeostasis and mood disorders."
01/01/2023 - "Prolactin-Releasing Peptide Contributes to Stress-Related Mood Disorders and Inhibits Sleep/Mood Regulatory Melanin-Concentrating Hormone Neurons in Rats."