alpha-hydroxyisocaproic acid

alpha-hydroxy analog of leucine; RN given refers to cpd without isomeric designation

Also Known As:

2-hydroxyisocaproic acid; alpha-hydroxyisocaproic acid, (R)-isomer; alpha-hydroxyisocaproic acid, (S)-isomer; alpha-hydroxyisocaproic acid, calcium (2:1) salt, (S)-isomer; alpha-hydroxyisocaproic acid, monosodium salt

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Rautemaa-Richardson, Riina: 1 article (01/2021)
2.	Richardson, Malcolm: 1 article (01/2021)
3.	Sakko, Marjut: 1 article (01/2021)
4.	Sakko, Samuli: 1 article (01/2021)
5.	Sorsa, Timo: 1 article (01/2021)

Related Diseases

1.	Weight Gain 05/01/1979 - "Using a completely defined liquid diet it was found that weight gain of germfree rats was well maintained and comparable to that of conventional rats when 1.5 M equivalents of DL-alpha-hydroxyisocaproic acid was substituted for L-leucine in the diet. "
2.	Short Bowel Syndrome 01/01/1987 - "Furthermore, the urine of a patient with an established short bowel syndrome contained a wide variety of bacterial amino acid metabolites, including 2-hydroxyisocaproic acid (2-HICA). "
3.	Periodontal Diseases (Periodontal Disease) 01/01/2021 - "Antibacterial Activity of 2-Hydroxyisocaproic Acid (HICA) Against Obligate Anaerobic Bacterial Species Associated With Periodontal Disease." 01/01/2021 - "In conclusion, topical use of 2-hydroxyisocaproic acid could eventually be a well-tolerated and useful method in the therapy of patients with difficult-to-treat periodontal disease or other superficial infections to avoid unnecessary antibiotic use and the emergence of antibiotic resistance."
4.	Infections 01/01/2021 - "In conclusion, topical use of 2-hydroxyisocaproic acid could eventually be a well-tolerated and useful method in the therapy of patients with difficult-to-treat periodontal disease or other superficial infections to avoid unnecessary antibiotic use and the emergence of antibiotic resistance."

Related Drugs and Biologics

1.	Leucine (L-Leucine)
2.	Anti-Bacterial Agents (Antibiotics)
3.	Amino Acids

Related Therapies and Procedures

1.	Therapeutics