alliin lyase (alliinase)

06/01/2011 - "Co-localization of the fluorescent conjugate with bioluminescence was observed for intraperitoneal tumors while nonconjugated alliinase did not accumulate. "
12/01/2003 - "After the mAb-alliinase conjugate was bound to target tumor cells, the substrate, alliin, was added. "
12/01/2003 - "Inhibition of tumor growth by a novel approach: in situ allicin generation using targeted alliinase delivery."
04/20/2012 - "One of the abzymes, VHHC10, showed the highest activity that can be inhibited by Ab1 VHHA4 and alliinase competitive inhibitor penicillamine and significantly suppressed the B16 tumor cell growth in the presence of alliin in vitro. "
06/01/2011 - "Treatment of tumor bearing mice with daidzein-alliinase and alliin effectively attenuated tumor progression during the first 12 days while a 5-fold increase in bioluminescence was detected in placebo-treated animals. "

02/01/2010 - "Therapy of murine pulmonary aspergillosis with antibody-alliinase conjugates and alliin."

02/01/2005 - "Alliinase was conjugated to the monoclonal antibody rituximab, which recognizes the CD20 antigen, and the resulting conjugate was targeted to CD20+ B chronic lymphocytic leukemia (B-CLL) and other B-cell lymphomas. "

02/01/2005 - "Alliinase was conjugated to the monoclonal antibody rituximab, which recognizes the CD20 antigen, and the resulting conjugate was targeted to CD20+ B chronic lymphocytic leukemia (B-CLL) and other B-cell lymphomas. "

01/01/2021 - "Increase of alliinase stability and its activity are of paramount importance in various applications relying on its use for in-situ synthesis of allicin or its analogues, e.g., pulmonary drug delivery, treatment of superficial injuries, or urease inhibitors in fertilizers. "