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dansylarginine N-(3-ethyl-1,5-pentanediyl)amide
fluorescent inhibitor of thrombin; structure
Also Known As:
DAPA Dns-Arg; Piperidine, 1-(5-((aminoiminomethyl)amino)-2-(((5-(dimethylamino)-1-naphthalenyl)sulfonyl)amino)-1-oxopentyl)-4-ethyl-, (S)-
Networked:
2
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Amino Acids, Peptides, and Proteins: 1
Amino Acids: 30675
Essential Amino Acids: 1152
Arginine: 11940
dansylarginine N-(3-ethyl-1,5-pentanediyl)amide: 2
Basic Amino Acids: 178
Arginine: 11940
dansylarginine N-(3-ethyl-1,5-pentanediyl)amide: 2
Diamino Amino Acids: 101
Arginine: 11940
dansylarginine N-(3-ethyl-1,5-pentanediyl)amide: 2
Organic Chemicals: 133
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Aromatic Hydrocarbons: 291
Polycyclic Aromatic Hydrocarbons: 2020
Naphthalenes: 18
Dansyl Compounds
dansylarginine N-(3-ethyl-1,5-pentanediyl)amide: 2
Sulfur Compounds: 278
Sulfones: 534
Dansyl Compounds
dansylarginine N-(3-ethyl-1,5-pentanediyl)amide: 2
Polycyclic Compounds: 6
Polycyclic Aromatic Hydrocarbons: 2020
Naphthalenes: 18
Dansyl Compounds
dansylarginine N-(3-ethyl-1,5-pentanediyl)amide: 2
Related Diseases
1.
Neuroblastoma
08/05/1983 - "
Thrombin, the central regulatory enzyme in coagulation, when incubated in nanomolar concentrations with murine neuroblastoma cells produced a rapid and marked increase in tritiated guanosine 3',5'-monophosphate (cyclic GMP) formation that was blocked by hirudin and competitively antagonized by dansylarginine N-(3-ethyl-1,5-pentanediyl)amide.
"
2.
Neoplasms (Cancer)
11/01/1981 - "
Inhibition of the platelet-aggregating activity of two human adenocarcinomas of the colon and an anaplastic murine tumor with a specific thrombin inhibitor, dansylarginine N-(3-ethyl-1,5-pentanediyl)amide.
"
3.
Adenocarcinoma
11/01/1981 - "
Inhibition of the platelet-aggregating activity of two human adenocarcinomas of the colon and an anaplastic murine tumor with a specific thrombin inhibitor, dansylarginine N-(3-ethyl-1,5-pentanediyl)amide.
"
Related Drugs and Biologics
1.
Thrombin
2.
Hirudins
3.
Cyclic GMP
4.
Guanosine
5.
Enzymes