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tetralol

structure

Also Known As:

1,2,3,4-tetrahydro-2-naphthol

Networked: 8 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Naphthalenes: 18
        Tetrahydronaphthalenes: 1
        Tetralones: 5
        tetralol: 8
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Naphthalenes: 18
    - Tetrahydronaphthalenes: 1
      - Tetralones: 5
        tetralol: 8

Experts

1.	Alza, Lía: 2 articles (05/2022 - 01/2019)
2.	Cantí, Carles: 2 articles (05/2022 - 01/2019)
3.	Herreros, Judit: 2 articles (05/2022 - 01/2019)
4.	Visa, Anna: 2 articles (05/2022 - 01/2019)
5.	Aguiar, Talita Ferreira: 1 article (04/2021)
6.	Lacruz, Rodrigo S: 1 article (04/2021)
7.	Mitaishvili, Erna: 1 article (04/2021)
8.	Souza Bomfim, Guilherme H: 1 article (04/2021)
9.	López-Ortega, Ricard: 1 article (01/2019)
10.	Maiques, Oscar: 1 article (01/2019)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2019 - "In vivo studies in glioblastoma (GBM) murine xenografts have shown that drugs able to block TTCC in vitro (such as tetralol derivatives mibefradil/NNC-55-096, or different 3,4-dihydroquinazolines) slow tumor progression. " 05/01/2022 - "Mibefradil and NNC-55-0396, tetralol derivatives with a proven -ability to block T-type calcium channels in excitable cells, reduce cancer cell viability in vitro, causing cell death. "
2.	Glioblastoma (Glioblastoma Multiforme) 05/01/2022 - "Tetralol derivative NNC-55-0396 induces glioblastoma cell death by activating IRE1α, JNK1 and calcium signaling." 01/01/2019 - "In vivo studies in glioblastoma (GBM) murine xenografts have shown that drugs able to block TTCC in vitro (such as tetralol derivatives mibefradil/NNC-55-096, or different 3,4-dihydroquinazolines) slow tumor progression. "
3.	Hypertension (High Blood Pressure) 04/30/2021 - "Mibefradil is a tetralol derivative originally developed as an antagonist of T-type voltage-gated calcium (Ca2+) channels to treat hypertension when used at nanomolar dosage. " 12/01/1998 - "Mibefradil, a tetralol derivative, is a new long-acting calcium antagonist used for the treatment of patients with hypertension and chronic stable angina pectoris. " 06/01/1998 - "Mibefradil, the first member of the tetralol derivatives, a new class of calcium antagonists, is used for the treatment of hypertension and angina pectoris. "
4.	Cataract (Cataracts) 01/01/1946 - "Production of cataracts in rats with beta tetralol." 05/01/1949 - "Production of cataract in rats by beta-tetralol and other derivatives of naphthalene."
5.	Stable Angina 12/01/1998 - "Mibefradil, a tetralol derivative, is a new long-acting calcium antagonist used for the treatment of patients with hypertension and chronic stable angina pectoris. "

Related Drugs and Biologics

1.	Mibefradil
2.	Calcium
3.	T-Type Calcium Channels (T-Type Calcium Channel)
4.	NNC 55-0396
5.	naphthalene