prunasin

cyanogenic glycoside; RN given refers to cpd without isomeric designation

Also Known As:

(R)-prunasin; benzeneacetonitrile, alpha-(beta-D-glucopyranosyloxy)-; mandelonitrile-beta-glucoside; prulaurasin; prunasin, (R)-isomer; prunasine

Networked: 14 relevant articles (2 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Nitriles: 227
  - prunasin: 14

Experts

1.	Chen, Jiamei: 2 articles (02/2022 - 12/2020)
2.	Liu, Ping: 2 articles (02/2022 - 12/2020)
3.	Liu, Wei: 2 articles (02/2022 - 12/2020)
4.	Xu, Ying: 2 articles (02/2022 - 12/2020)
5.	Zhang, Dingqi: 2 articles (02/2022 - 12/2020)
6.	Cheng, Xuemei: 1 article (02/2022)
7.	Fang, Qinqin: 1 article (02/2022)
8.	Qi, Shenglan: 1 article (02/2022)
9.	Wang, Changhong: 1 article (02/2022)
10.	Wang, Yongli: 1 article (02/2022)

Related Diseases

1.	Inflammation (Inflammations) 11/01/2018 - "Prunasin has biological properties such as anti-inflammation, but plant extraction and chemical synthesis are impractical. " 02/08/2017 - "Twenty-three KBGY compounds were detected in plasma, including gallic acid, prunasin, paeoniflorin, and azelaic acid, which have been reported to be effective for inflammation. "
2.	Arthritis (Polyarthritis) 01/01/2019 - "Protective Effects of Prunasin A against the Differentiation of Osteoclasts and Destruction of Cartilage via the Receptor Activator of Nuclear Factor-Kappa-Β Ligand/Mitogen-Activated Protein Kinase/Osteoprotegerin Pathway in a Rat Model of Arthritis."
3.	Liver Cirrhosis (Hepatic Cirrhosis) 05/01/2022 - "However, the pharmacokinetic and anti-liver fibrosis effects of Amy and its enzyme metabolite prunasin (Pru) in vivo have not been studied and compared, and studies on Pru are limited. " 05/01/2022 - "Pharmacokinetics and anti-liver fibrosis characteristics of amygdalin: Key role of the deglycosylated metabolite prunasin." 12/01/2020 - "Emodin, rhein, aloe-emodin and prunasin were main active ingredients of EF, which provides a potential drug for the treatment of liver fibrosis."
4.	Pneumonia (Pneumonitis) 07/01/2015 - "To establish a LC-MS/MS method to determine the concentrations of liquiritin, glycyrrhizin, glycyrrhetinic acid, amygdalin, amygdalin prunasin, ephedrine, pseudoephedrine and methylephedrine of Maxing Shigan decoction in rat plasma, and study the differences on their pharmacokinetic process in normal rats and RSV pneumonia model rats. "
5.	Neoplasms (Cancer) 05/01/2013 - "Amygdalin is one of a number of nitrilosides, the natural cyanide‑containing substances abundant in the seeds of plants of the prunasin family that are used to treat cancer and relieve pain. " 10/01/1981 - "Amygdalin (Laetrile) and prunasin beta-glucosidases: distribution in germ-free rat and in human tumor tissue." 08/01/2006 - "Amygdalin is one of the nitrilosides, natural cyanide-containing substances abundant in the seeds of plants of the prunasin family that have been used to treat cancers and relieve pain. " 01/01/2020 - "Other substances in these groups with pronounced biological activity (including anti-tumor) are the hydrolyzed nitrile groups by Prunasin, Lucumin, Vicianin, Sambunigrin, Dhurrin, Taxiphyllin, Zierin, Preteacin, p-Glucosyloxymandelonitrile, Linamarin, Lotaustralin, Acaciapetalin, Triglochinin, Dejdaclin, Tetraphyllin A, Tetrallin B, Gynocardin etc., to their amide/carboxylic acid."

Related Drugs and Biologics

1.	Osteoprotegerin
2.	Mitogen-Activated Protein Kinases
3.	Ligands
4.	Gallic Acid
5.	peoniflorin
6.	azelaic acid (Azelex)
7.	Amygdalin (Laetrile)
8.	Pseudoephedrine
9.	Glycyrrhizic Acid (Glycyrrhizin)
10.	Glycyrrhetinic Acid (Po 12)