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hexamidine

Also Known As:
1,6-di(para-amidinophenoxy)hexane; 1,6-di-(4-amidinophenoxy)hexane; Désomédine; Hexaseptine; Hexomedin; Hexomedin N; Hexomedine; Hexomédine; Laryngomedin N; Ophtamedine; hexamidine dihydrochloride; hexamidine diisethionate; hexamidine isethionate; Benzenecarboximidamide, 4,4'-(1,6-hexanediylbis(oxy))bis-
Networked: 33 relevant articles (2 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Amsler, Emmanuelle: 1 article (11/2021)
2. Barbaud, Annick: 1 article (11/2021)
3. Castagna, Julie: 1 article (11/2021)
4. Chantran, Yannick: 1 article (11/2021)
5. Kurihara, Flore: 1 article (11/2021)
6. Le Seac'h, Agathe: 1 article (11/2021)
7. Soria, Angèle: 1 article (11/2021)
8. Bischoff, Markus: 1 article (11/2020)
9. Elhawy, Mohamed Ibrahem: 1 article (11/2020)
10. Gunaratnam, Gubesh: 1 article (11/2020)

Related Diseases

1. Epilepsy (Aura)
2. Anterior Uveitis
3. Cysts
02/01/1995 - "As a result of these data, a kinetic study carried out on propamidine, hexamidine, and octamidine demonstrated that the amoebicidal effects resulted from two events: the diffusion of molecules through the plasma membrane or the double wall of trophozoites or cysts, respectively, and the lethal effects of molecules on amoebic protoplasm. "
09/01/2019 - "With the diamidines, the presence of BAC in the propamidine drops was responsible for the activity against Acanthamoeba spp. Hexamidine drops without BAC showed good activity against trophozoites, and the biguanides polyhexamethylene biguanide, chlorhexidine, alexidine, and octenidine all showed excellent activity against trophozoites and cysts of both species. "
08/13/2022 - "Here, we tested the capability of the off-label anti-amoebic drugs chlorhexidine (CH; 0.1%), dibromopropamidine diisethionate (DD; 0.1%), hexamidine diisethionate (HD; 0.1%), miltefosine (MF; 0.0065%), natamycin (NM; 5%), polyhexamethylene biguanide (PHMB; 0.02%), povidone iodine (PVPI; 1%), and propamidine isethionate (PD; 0.1%) to suppress trophozoite formation of Acantamoeba castellanii and Acanthamoeba hatchetti cysts on non-nutrient agar Escherichia coli plates. "
11/01/2020 - "The purpose of this study was to analyze the concentration-dependent effects of biguanides (polyhexamethylene biguanide [PHMB], chlorhexidine [CH]); diamidines (hexamidine-diisethionate [HD], propamidine-isethionate [PD], dibromopropamidine-diisethionate [DD]); natamycin (NM); miltefosine (MF); povidone iodine (PVPI), and chlorin e6 PDT on Acanthamoeba trophozoites and cysts, in vitro. "
4. Acne Vulgaris
5. Acanthamoeba Keratitis

Related Drugs and Biologics

1. Phenobarbital (Luminal)
2. benzobarbital
3. Fluoroquinolones
4. Albendazole (Albenza)
5. Trimethadione (Tridione)
6. Steroids
7. Phenytoin (Dilantin)
8. Diazepam (Valium)
9. Chlordiazepoxide (Elenium)
10. Carbamazepine (Tegretol)

Related Therapies and Procedures

1. Debridement
2. Hydrophilic Contact Lenses (Hydrophilic Contact Lens)
3. Contact Lenses
4. Aftercare (After-Treatment)