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fluoro-7,12-dimethylbenz(a)anthracene
1-2,-,5- & 11-fluoro cpds have been tested as mutagens & carcinogens
Also Known As:
F-DMBA
Networked:
2
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Aromatic Hydrocarbons: 291
Polycyclic Aromatic Hydrocarbons: 2020
Benz(a)Anthracenes: 2
9,10-Dimethyl-1,2-benzanthracene: 979
fluoro-7,12-dimethylbenz(a)anthracene: 2
Polycyclic Compounds: 6
Polycyclic Aromatic Hydrocarbons: 2020
Benz(a)Anthracenes: 2
9,10-Dimethyl-1,2-benzanthracene: 979
fluoro-7,12-dimethylbenz(a)anthracene: 2
Related Diseases
1.
Neoplasms (Cancer)
01/01/1992 - "
The amounts of the 4.6-Kb and 1.8-Kb restriction fragments generated by HpaII digestion in pituitary tissues were influenced by estrogen, with an increase in these fragments in normal pituitary, MtT/F4, and MtT/F-DMBA tumors after estrogen treatment.
"
01/01/1992 - "
Northern analysis showed increased PRL mRNA expression in estrogen-treated pituitary and in MtT/F4 and MtT/F-DMBA tumors.
"
12/01/1990 - "
MtT/F-DMBA tumors expressed prolactin (PRL), growth hormone (GH), and adrenocorticotropin (ACTH) mRNAs.
"
2.
Pituitary Neoplasms (Pituitary Adenoma)
12/01/1990 - "
A new transplantable rat pituitary tumor was induced in F344 female rats with dimethylbenz(a)anthracene and estrogen (MtT/F-DMBA) and studied for 20 serial transplant generations.
"
Related Drugs and Biologics
1.
Estrogens (Estrogen)
2.
Growth Hormone (Somatotropin)
3.
Messenger RNA (mRNA)
4.
Prolactin
5.
Adrenocorticotropic Hormone (ACTH)
6.
anthracene