cinnamyl alcohol dehydrogenase

NADP-dependent enzyme that catalyzes the reversible conversion of p-hydroxycinnamaldehydes to their corresponding alcohols, leading to the biosynthesis of lignin in plants

Networked: 13 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Bi, Yang: 1 article (05/2022)
2.	Gong, Di: 1 article (05/2022)
3.	Li, Zhicheng: 1 article (05/2022)
4.	Prusky, Dov: 1 article (05/2022)
5.	Wang, Bin: 1 article (05/2022)
6.	Xie, Pengdong: 1 article (05/2022)
7.	Xu, Xiaoqin: 1 article (05/2022)
8.	Xue, Sulin: 1 article (05/2022)
9.	Zheng, Xiaoyuan: 1 article (05/2022)
10.	Afifah, Anis: 1 article (03/2022)

Related Diseases

1.	Wounds and Injuries (Trauma) 02/01/1994 - "cv Fenman) leaf cinnamyl alcohol dehydrogenase (CAD, EC 1.1.1.195) was examined in relation to its role in regulating the composition of defensive lignin induced at wound margins. " 09/01/1999 - "Molecular characterisation and expression of a wound-inducible cDNA encoding a novel cinnamyl-alcohol dehydrogenase enzyme in lucerne (Medicago sativa L.)" 05/01/2022 - "Here, we found that chitosan sprays increased the activities of 4-coumaric acid-coenzyme A ligase, cinnamyl-CoA reductase and cinnamyl alcohol dehydrogenase, and elevated the levels of p-coumaryl alcohol, coniferyl alcohol, sinapyl alcohol and lignin at wounds. "
2.	Disease Resistance 03/09/2022 - "Among these, six phosphoproteins were uniquely identified in resistant plants including cinnamyl alcohol dehydrogenase 1 (CAD1), mitogen-activated protein kinase kinase kinase 18 (MAPKKK18), phospholipase D delta (PLDDELTA), nicotinamide adenine dinucleotide transporter 1 (NDT1), B3 domain-containing transcription factor VRN1, and disease resistance protein RPM1 (RPM1). " 08/06/2020 - "By comparison of protein expression and gene transcription, LOC_Os01g06600 (ACX, a glutaryl-CoA dehydrogenase), LOC_Os09g23560 (CAD, a cinnamyl-alcohol dehydrogenase), LOC_Os03g39850 (GST, a glutathione S-transferase) and LOC_Os11g11960 (RPM1, a disease resistance protein) on the alpha-linolenic acid metabolism, phenylpropanoid biosynthesis, glutathione metabolism and plant-pathogen interaction pathways, respectively, were all associated with disease defense and identified to be significantly down-regulated in the compatible interaction of NPB with nematodes, while the corresponding genes were remarkably up-regulated in the roots of a resistant rice accession "Khao Pahk Maw" with infection of nematodes. "
3.	Infections 01/01/2018 - "Quantitative RT-PCR analysis showed that expression levels of SofDIR16 (sugarcane dirigent16) and SofCAD (sugarcane cinnamyl alcohol dehydrogenase) were higher in the smut resistant My 55-14 cultivar than in the sensitive B 42231 cultivar prior to infection. " 08/06/2020 - "By comparison of protein expression and gene transcription, LOC_Os01g06600 (ACX, a glutaryl-CoA dehydrogenase), LOC_Os09g23560 (CAD, a cinnamyl-alcohol dehydrogenase), LOC_Os03g39850 (GST, a glutathione S-transferase) and LOC_Os11g11960 (RPM1, a disease resistance protein) on the alpha-linolenic acid metabolism, phenylpropanoid biosynthesis, glutathione metabolism and plant-pathogen interaction pathways, respectively, were all associated with disease defense and identified to be significantly down-regulated in the compatible interaction of NPB with nematodes, while the corresponding genes were remarkably up-regulated in the roots of a resistant rice accession "Khao Pahk Maw" with infection of nematodes. "
4.	Skeletal Abnormalities Mandibular Hypoplasia Auditory Canal Atresia Short Stature 04/01/2013 - "The expression of PHENYLALANINE AMMONIA LYASE2, CINNAMATE 4-4HYDROXYLASE, and CINNAMYL ALCOHOL DEHYDROGENASE were repressed in SAMs over-expressing BnSTM. " 10/30/2018 - "The mechanisms underlying the B-induced alleviation of Al-toxicity unveiled by 2-DE technique could be summarized as follows: a) remodeling of cell wall by reducing the synthesis of lignin (sugar ATP Binding Cassette (ABC) transporter ATPase and cinnamyl alcohol dehydrogenase) and increasing the modification of cell wall (UDP-forming); b) enhancing the abundances of proteasomes and turnover of dysfunctional proteins (proteasome or protease); c) increasing the abundance of stress response proteins, such as alcohol dehydrogenase, S-adenosylmethionine synthetase (SAMS) and glycosyl hydrolase; d) reinforcing cellular biological regulation and signal transduction (calreticulin-1). "
5.	Sclerosis 11/01/2021 - "Additionally, some DEGs associated with cell wall components, i.e., cellulose synthase/cellulose synthase like protein (CESA/CSL), fasciclin-like arabinogalactan (APG), leucine-rich repeat protein (LRR) and lignin biosynthesis enzymes including phenylalanine ammonia-lyase, S-adenosyl-L-methionine-dependent methyltransferases, 4-coumarate-CoA ligase, cinnamoyl CoA reductase, cinnamyl alcohol dehydrogenase, catalase, peroxiredoxin/peroxidase were found to control cell wall sclerosis. "

Related Drugs and Biologics

1.	Lignin
2.	Proteins (Proteins, Gene)
3.	Phenylalanine (L-Phenylalanine)
4.	Enzymes
5.	Catalase
6.	4-coumarate-CoA ligase
7.	cinnamoyl CoA reductase
8.	Peroxiredoxins
9.	Glutaryl-CoA Dehydrogenase
10.	Chitosan