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Ro 363
Also Known As:
1,2-Benzenediol, 4-(3-((2-(3,4-dimethoxyphenyl)ethyl)amino)-2-hydroxypropoxy)-, (+-)-; 1-(3,4-dimethoxyphenethylamino)-3-(3,4-dihydroxyphenoxy)-2-propanol; RO363; Ro-363
Networked:
2
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Amines: 4871
Amino Alcohols: 20
Propanolamines: 4
Ro 363: 2
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Aromatic Hydrocarbons: 291
Benzene Derivatives: 17
Phenols: 677
Catechols: 121
Ro 363: 2
Alcohols: 595
Amino Alcohols: 20
Propanolamines: 4
Ro 363: 2
Propanols: 3
Propanolamines: 4
Ro 363: 2
Related Diseases
1.
Tachycardia (Tachyarrhythmias)
07/01/1983 - "
Pretreatment of anaesthetized rabbits with hexamethonium bromide (10 mg/kg i.v.) did not markedly affect the tachycardia elicited by i.c.v. RO363 and reduced the response to i.c.v. (-)-isoprenaline in only one out of five experiments.
"
07/01/1983 - "
Pretreatment with guanethidine sulphate (5 mg/kg i.v.) reduced but did not abolish the tachycardia elicited by i.c.v. RO363, whereas heart rate responses to i.c.v. (-)-isoprenaline were unaffected.
"
2.
Myocardial Infarction
12/01/1999 - "
Using a rat model of cardiac failure, induced by myocardial infarction (MI), we compared the desensitization and resensitization of responses to CGP 12177A with those to isoprenaline and RO 363 in left (LA) and right atria (RA).
"
3.
Heart Failure
12/01/1999 - "
Using a rat model of cardiac failure, induced by myocardial infarction (MI), we compared the desensitization and resensitization of responses to CGP 12177A with those to isoprenaline and RO 363 in left (LA) and right atria (RA).
"
Related Drugs and Biologics
1.
Isoproterenol (Isoprenaline)
2.
Hexamethonium (Hexamethonium Bromide)
3.
Guanethidine
4.
CGP 12177