NSC 290205

homo-aza-steroidal ester of p-bis(2-chloroethyl) amino phenyl acetic acid; RN given refers to (3beta,5alpha)-isomer; structure

Also Known As:

3-hydroxy-13-amino-13,17-seco-5alpha--androstan-17-oic-13,17-lactam p-N,N-bis(2-chloroethyl)aminophenylacetate; 3-hydroxy-13-amino-13,17-secoandrostan-17-oic-13,17-lactam-4-bis(2-chloroethyl)aminophenylacetate; 4 (N,N-bis(2-chloroethyl)amino)phenylacetate 3-hydroxy-17-aza-D-homoandrostan-17-one; NSC 290205, (3alpha,5alpha)-isomer; NSC 620482; NSC-290205; NSC-620482; NSC-71964

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

Neoplasms (Cancer)

01/01/1982 - "Activity of 3 beta-hydroxy-13 alpha-amino-13,17-seco-5 alpha-androstane-17-oic-13,17-lactam(p-(bis(2-chloroethyl)amino)-phenyl) acetate(NSC 290205) in murine solid tumors."
03/01/1984 - "The modified steroidal alkylating agent 3 beta-hydroxy-13 alpha-amino-13,17-seco-5 alpha-androstan-17-oic-13,17-lactam [p-[bis(2-chloroethyl)amino]phenyl]acetate (NSC 290205) is active in treating the LX-1 lung and MX-1 breast xenografts as well as a number of rodent tumors. "

Related Drugs and Biologics

1.	Alkylating Agents
2.	Acetates (Acetic Acid Esters)
3.	phenyl acetate
4.	3 beta-hydroxy-13 alpha-amino-13,17-seco-5 alpha-androstan-17-oic-13,17-lactam