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2-hydroxypyridine

cpd is keto-enol tautomer

Also Known As:

2-hydroxypyridine sodium salt; 2-pyridinone; 2-pyridone; 2(lH)-pyridinone

Networked: 23 relevant articles (2 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyridines: 88
    - Pyridones: 14
      - 2-hydroxypyridine: 23

Experts

1.	Almqvist, Fredrik: 2 articles (12/2014 - 04/2013)
2.	Kang, Sangyoon: 1 article (01/2022)
3.	Kang, Sunah: 1 article (01/2022)
4.	Kim, Yumin: 1 article (01/2022)
5.	Lee, Byung Hun: 1 article (01/2022)
6.	Lee, Yan: 1 article (01/2022)
7.	Park, Hye Yoon: 1 article (01/2022)
8.	Song, Youngjun: 1 article (01/2022)
9.	Alarcón-Miranda, Carlos: 1 article (10/2021)
10.	Cho, Young Hwa: 1 article (10/2021)

Related Diseases

1.	Infections 12/30/2014 - "Thus, 2-pyridone amides may represent a class of drugs that can specifically inhibit C. trachomatis infection. " 06/06/2014 - "CG400549, a Staphylococcus-specific 2-pyridone compound that inhibits the enoyl-acyl carrier protein reductase (FabI), has recently been shown to possess human efficacy for the treatment of methicillin-resistant Staphylococcus aureus infections, which constitute a serious threat to human health. "
2.	Urinary Tract Infections (Urinary Tract Infection) 10/01/1996 - "ABT-719, which represents the new 2-pyridone compound class, has promise for the treatment of urinary tract infections, as suggested by the significant efficacy seen against experimental pyelonephritis caused by E. "
3.	Pyelonephritis 10/01/1996 - "Efficacy of ABT-719, a 2-pyridone antimicrobial, against enterococci, Escherichia coli, and Pseudomonas aeruginosa in experimental murine pyelonephritis." 10/01/1996 - "ABT-719, which represents the new 2-pyridone compound class, has promise for the treatment of urinary tract infections, as suggested by the significant efficacy seen against experimental pyelonephritis caused by E. "
4.	COVID-19 10/26/2022 - "Insight into designing of 2-pyridone derivatives for COVID-19 drug discovery - A computational study." 02/01/2021 - "This work has identified 2-pyridone natural products with calculated potent inhibitory activity against SARS-CoV-2 Mpro and with desirable drug-like properties, which may lead to the rapid discovery of a treatment for COVID-19." 05/22/2023 - "This study aimed to evaluate the antiviral activity of 2-pyridone PIM1 inhibitor against SARS-CoV-2 and its potential role in hindering the progression of COVID-19. " 10/26/2022 - "In the present investigation, twenty-three 2-pyridone synthetic derivatives (P1-P23) have been theoretically tested for their suitability as potential inhibitors for COVID-19 main protease through DFT, molecular docking, and molecular dynamics simulations. "
5.	Parkinson Disease (Parkinson's Disease) 04/15/2013 - "In a recent study we discovered that a ring-fused 2-pyridone compound triggered fibrillization of a key protein in Parkinson's disease, α-synuclein. "

Related Drugs and Biologics

1.	Oxidoreductases (Dehydrogenase)
2.	Acyl Carrier Protein
3.	CG 400549
4.	ABT 719
5.	Synucleins
6.	Proteins (Proteins, Gene)
7.	Antiviral Agents (Antivirals)
8.	Peptidomimetics
9.	Succinic Acid (Succinate)
10.	AMPA Receptors (AMPA Receptor)

Related Therapies and Procedures

1.	Photochemotherapy (Photodynamic Therapy)
2.	Phototherapy (Light Therapy)