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phallacidin

bicyclic heptapeptide from Amanita (along with phalloidin)

Networked: 16 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Macrocyclic Compounds: 15
  - Cyclic Peptides: 530
    - phallacidin: 16
Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Cyclic Peptides: 530
    - phallacidin: 16

Experts

1.	Hagelauer, Nadine: 1 article (06/2015)
2.	Pabst, Andreas M: 1 article (06/2015)
3.	Walter, Christian: 1 article (06/2015)
4.	Ziebart, Thomas: 1 article (06/2015)
5.	Andreev, Oleg A: 1 article (11/2011)
6.	Engelman, Donald M: 1 article (11/2011)
7.	Reshetnyak, Yana K: 1 article (11/2011)
8.	Wijesinghe, Dayanjali: 1 article (11/2011)
9.	Dudek, Steven M: 1 article (08/2007)
10.	Garcia, Joe G N: 1 article (08/2007)

Related Diseases

1.	Wounds and Injuries (Trauma) 04/01/1987 - "The development of microfilaments correlated with increased NBD-phallacidin fluorescence of fibrocytes adjacent to the wound as compared with fibrocytes farther removed from the site of injury. " 06/01/2015 - "In addition to the 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl 2H-tetrazolium bromide (MTT) vitality test, the migration capacity was analysed by scratch wound assay and the morphological architecture of the treated cells by phallacidin staining. " 01/01/1987 - "With the use of specific fluorescent probe (NBD-phallacidin), the distribution of actin filaments are compared in normal dermis and in several wound contraction models, including open and burn wounds and full and thin-thickness skin autografts. " 03/01/1984 - "An experimentally induced wound made in a confluent monolayer culture of porcine thoracic aortic endothelial cells (ECs) was studied 22 hours after wounding using 7-nitrobenz-2-oxa-1,3-diazole (NBD) phallacidin and immunofluorescence microscopy to localize actin and myosin containing microfilament (MF) bundles. "
2.	Neoplasms (Cancer) 11/29/2011 - "The phallacidin cargoes were conjugated to pHLIP and shown to selectively inhibit the proliferation of cancer cells in a concentration-dependent manner at low pH." 10/01/1993 - "Similarly, resting and fMLP-stimulated levels of F-actin in cancer patients' leukocytes as assessed by NBD-phallacidin staining did not differ significantly from those of normal leukocytes. " 04/01/1985 - "The same tumors were examined by making standard cell spots on plastic or glass surfaces, and examining these by phase and reflection contrast microscopy, fluorescent microscopy after anti-actin and phallacidin staining and transmission electron microscopy. "
3.	Burns 01/01/1987 - "With the use of specific fluorescent probe (NBD-phallacidin), the distribution of actin filaments are compared in normal dermis and in several wound contraction models, including open and burn wounds and full and thin-thickness skin autografts. " 12/01/1994 - "Endothelial F-actin was stained with NBD-phallacidin in regular sequence to find out the details of endothelial healing after alkali burn. "
4.	Blister (Bulla) 09/01/1987 - "Fluorescence microscopy of nitrobenzooxadizole-phallacidin-labeled cells indicated that blebs contained filamentous actin and that microfilament bundles remained primarily on the substratum side of blebbed cells. " 12/01/1982 - "Cytoskeletal staining of blebs with NBD- phallacidin, a fluorescent probe specific for F-actin, indicated that loss of the bulk of the F-actin cytoskeleton accompanied the release of the natural constraints on later diffusion observed on blebs. "
5.	Hyperoxia 08/10/2007 - "Pretreatment of HPAECs with the actin-stabilizing agent phallacidin attenuated hyperoxia-induced cortical actin thickening and ROS production, whereas cytochalasin D and latrunculin A enhanced basal and hyperoxia-induced ROS formation. "

Related Drugs and Biologics

1.	Actins (F Actin)
2.	Fluorescent Dyes (Fluorescent Probes)
3.	Cytochalasin D
4.	Plastics
5.	Myosins (Myosin)
6.	Lipids
7.	Excipients (Suspending Agents)
8.	Concanavalin A
9.	Bromides
10.	Alkalies

Related Therapies and Procedures

1.	Vitrectomy