penilloic acid

formed from decarboxylation of penicilloic acid; structure

Also Known As:

5,5-dimethyl-2-(((phenylacetyl)amino)methyl)-1,3-thiazolidine-4-carboxylic acid; benzylpenilloic acid; penilloate; 4-Thiazolidinecarboxylic acid, 5,5-dimethyl-2-(((2-phenylacetyl)amino)methyl)-

Networked: 5 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amides: 2428
  - Lactams: 2198
    - beta-Lactams: 2386
      - Penicillins: 16651
        Penicillin G: 1462
        penilloic acid: 5
- Sulfur Compounds: 278
  - beta-Lactams: 2386
    - Penicillins: 16651
      - Penicillin G: 1462
        penilloic acid: 5
Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - beta-Lactams: 2386
      - Penicillins: 16651
        Penicillin G: 1462
        penilloic acid: 5

Experts

1.	Arribas-Poves, F: 1 article (01/2013)
2.	Blanca, M: 1 article (01/2013)
3.	Campos, J: 1 article (01/2013)
4.	DAP-Diater Group: 1 article (01/2013)
5.	Fernández, J: 1 article (01/2013)
6.	Torres, M J: 1 article (01/2013)

Related Diseases

1.	Hypersensitivity (Allergy) 01/01/2022 - "Penilloic acid is the chief culprit involved in non-IgE mediated, immediate penicillin-induced hypersensitivity reactions in mice." 09/01/1987 - "The reagents, penicillin, penicilloylpolylysine, benzyl penicilloate, and benzyl penilloate provide a safe and effective skin test for screening out the likelihood of severe allergic reactions to penicillin. " 01/01/1977 - "Positive skin test results using monovalent penicillin derivatives such as penicillin, penicilloate, penilloate, penicilloyl amide, penicilloyl-formyl-lysine, penicillamine, which cannot form a multivalent antigen with penicillyol specificity, indicated formation of other derivatives of importance in penicillin allergy, e.g., penicillamine protein conjugates. "
2.	Inflammation (Inflammations) 01/01/2022 - "This study revealed that penilloic acid was the chief culprit involved in penicillin-induced immediate NAHRs in mice, which mainly associated with direct stimulation of vascular hyperpermeability and exudative inflammation. "
3.	Immediate Hypersensitivity 01/01/2013 - "To synthesize and assess the diagnostic capacity of 2 new benzylpenicillin reagents in patients with immediate hypersensitivity reactions to B-lactams: benzylpenicilloyl octa-L-lysine (BP-OL) as the major determinant and benzylpenilloate (penilloate) as the minor determinant. "
4.	Anaphylaxis (Anaphylactic Shock) 01/01/1984 - "Eliciting IgE-mediated passive cutaneous anaphylactic reaction by synthetic D-benzylpenilloic acid analogs."

Related Drugs and Biologics

1.	Penicillins (Penicillin)
2.	Indicators and Reagents (Reagents)
3.	penicilloic acid
4.	Lysine (L-Lysine)
5.	Immunoglobulin E (IgE)
6.	Proteins (Proteins, Gene)
7.	Penicillin G (Benzylpenicillin)
8.	Penicillamine (Cuprimine)
9.	Lactams
10.	Antigens