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methylethylnitrosamine
Also Known As:
ethylmethylnitrosamine; ethylnitrosomethylamine; nitrosoethylmethylamine; nitrosomethylethylamine
Networked:
4
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Nitroso Compounds: 446
Nitrosamines: 1539
Dimethylnitrosamine: 872
methylethylnitrosamine: 4
Related Diseases
1.
Neoplasms (Cancer)
04/01/1982 - "
The remaining compounds, all of which can be considered true derivatives of nitrosomethylethylamine, were less potent than nitrosomethylbenzylamine but also induced a high incidence of tumors of the esophagus.
"
08/01/1986 - "
At low doses, N-nitrosomethylethylamine (NMEA) selectively produces liver tumors in rats, whereas beta-trideuterated NMEA also includes esophageal carcinomas under these conditions.
"
04/01/1991 - "
While N-nitrosoethylmethylamine (NEMA) is carcinogenic primarily for the liver, its beta-trideuterated derivative, N-nitroso( [2-D3]ethyl)methylamine (NEMA-d3), also produces a high incidence of tumors in the esophagus.
"
12/01/1981 - "
Nitrosomethylethylamine (NMEA) induced both hemangiosarcomas and hepatocellular carcinomas, together with some esophageal tumors, but must be considered a weaker carcinogen than the dimethyl or diethyl analogs, since a much higher dose was needed to achieve a comparable effect.
"
04/01/1982 - "
Deuterium-labeled nitrosomethylethylamine, in which deuterium replaces hydrogen on the beta-carbon atom of nitrosomethylethylamine, induced a high incidence of esophageal tumors as well as liver tumors after administration of identical doses.
"
2.
Hepatocellular Carcinoma (Hepatoma)
12/01/1981 - "
Nitrosomethylethylamine (NMEA) induced both hemangiosarcomas and hepatocellular carcinomas, together with some esophageal tumors, but must be considered a weaker carcinogen than the dimethyl or diethyl analogs, since a much higher dose was needed to achieve a comparable effect.
"
3.
Hemangiosarcoma (Angiosarcoma)
12/01/1981 - "
Nitrosomethylethylamine (NMEA) induced both hemangiosarcomas and hepatocellular carcinomas, together with some esophageal tumors, but must be considered a weaker carcinogen than the dimethyl or diethyl analogs, since a much higher dose was needed to achieve a comparable effect.
"
4.
Carcinoma (Carcinomatosis)
08/01/1986 - "
At low doses, N-nitrosomethylethylamine (NMEA) selectively produces liver tumors in rats, whereas beta-trideuterated NMEA also includes esophageal carcinomas under these conditions.
"
Related Drugs and Biologics
1.
Hydrogen
2.
Deuterium
3.
Carcinogens
4.
Carbon
5.
methylamine (methylammonium)