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2-imidazoline

RN given refers to parent cpd; structure

Also Known As:

2-imidazoline monohydrogen iodide; 4,5-dihydro-1H-imidazole

Networked: 3 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Imidazoles: 150
      - 2-imidazoline: 3

Experts

1.	Hage, David S: 1 article (08/2021)
2.	Suh, Kyungah: 1 article (08/2021)
3.	Weigand, Miranda: 1 article (08/2021)
4.	Woolfork, Ashley G: 1 article (08/2021)
5.	Han, Zhao: 1 article (03/2011)
6.	Hou, Sheng-Tao: 1 article (03/2011)
7.	Lin, Fu-Hong: 1 article (03/2011)
8.	Wang, Pei: 1 article (03/2011)
9.	Wang, Zhao-Wei: 1 article (03/2011)
10.	Zheng, Rong-Yuan: 1 article (03/2011)

Related Diseases

1.	Spinal Cord Injuries (Spinal Cord Injury) 03/04/2011 - "Our previous studies showed that ligands to type 2 imidazoline receptors (I(2)R) were effective in protecting spinal cord injury caused by experimental autoimmune encephalomyelitis (EAE), a mouse model of MS. In this study, we further examined the protective property of a very selective ligand of I(2)R, 2-(2-benzofuranyl) 2-imidazoline (2-BFI) against EAE. "
2.	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 03/04/2011 - "Our previous studies showed that ligands to type 2 imidazoline receptors (I(2)R) were effective in protecting spinal cord injury caused by experimental autoimmune encephalomyelitis (EAE), a mouse model of MS. In this study, we further examined the protective property of a very selective ligand of I(2)R, 2-(2-benzofuranyl) 2-imidazoline (2-BFI) against EAE. "
3.	Hypertension (High Blood Pressure) 08/05/2021 - "2-Imidazoline drugs are used in a variety of applications, such as the treatment of hypertension and opioid withdrawal. "
4.	Sickle Cell Anemia (Hemoglobin S Disease) 05/01/1983 - "Since this level of drug is lower than those reported for many other anti-sickling agents to achieve comparable effects, the 2-imidazoline class of compounds may provide important clues for the development of therapy for sickle cell anemia."

Related Drugs and Biologics

1.	Imidazoline Receptors
2.	Ligands
3.	Opioid Analgesics (Opioids)

Related Therapies and Procedures

1.	Therapeutics