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halopemide
structure
Also Known As:
R 34301; N-(2-(4-(5-chloro-2-oxo-1-benzimidazolinyl)piperidino)ethyl)-p-fluorobenzamide
Networked:
4
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Piperidines: 17
Domperidone: 783
halopemide: 4
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Benzimidazoles: 245
Domperidone: 783
halopemide: 4
Related Diseases
1.
Mental Disorders (Mental Disorder)
01/01/1984 - "
The resocializing and activating properties of halopemide were investigated in an open study and a double-blind study in 20 patients who had been hospitalized on account of various psychiatric disorders.
"
2.
Dyskinesias (Dyskinesia)
01/01/1981 - "
Acute dyskinesias, a neuroleptic-induced acute extrapyramidal syndrome, were elicited in squirrel monkeys by oxiperomide (1 mg/kg), tiapride (30 mg/kg), and halopemide (10 mg/kg).
"
01/01/1981 - "
Acute dyskinesias in monkeys elicited by halopemide, mezilamine and the "antidyskinetic" drugs, oxiperomide and tiapride.
"
3.
Parkinsonian Disorders (Parkinsonism)
02/22/1985 - "
Preliminary clinical findings indicate that halopemide lacks the ability to induce parkinsonism and may be an effective drug in the treatment of psychosis characterized by autism, emotional withdrawal or apathy.
"
4.
Vomiting
07/01/1987 - "
Both domperidone and halopemide, but not SCH 23,390, blocked the apomorphine-induced vomiting.
"
5.
Psychotic Disorders (Schizoaffective Disorder)
02/22/1985 - "
Preliminary clinical findings indicate that halopemide lacks the ability to induce parkinsonism and may be an effective drug in the treatment of psychosis characterized by autism, emotional withdrawal or apathy.
"
Related Drugs and Biologics
1.
Tiapride Hydrochloride
2.
Antipsychotic Agents (Antipsychotics)
3.
Domperidone (Domperidon)
4.
Apomorphine
5.
oxiperomide
6.
mezilamine