butoconazole (Femstat)

RN given refers to parent cpd; structure

Also Known As:

Femstat; butoconazole nitrate; 1-(4-(4-chlorophenyl)-2-(2,6-dichlorophenylthio)-n-butyl)-1H-imidazole; Femstal; Gynazole-1; Gynomyk; Mycelex-3; RS 35887; 1H-Imidazole, 1-(4-(4-chlorophenyl)-2-((2,6-dichlorophenyl)thio)butyl)-, (+/-)-

Networked: 28 relevant articles (6 outcomes, 8 trials/studies)

Relationship Network

Drug Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Imidazoles: 150
      - butoconazole: 28

Experts

1.	Bellagamba, Giuseppe: 1 article (12/2017)
2.	Campestre, Cristina: 1 article (12/2017)
3.	Carradori, Simone: 1 article (12/2017)
4.	Celia, Christian: 1 article (12/2017)
5.	De Luca, Elisa: 1 article (12/2017)
6.	Di Marzio, Luisa: 1 article (12/2017)
7.	Guglielmi, Paolo: 1 article (12/2017)
8.	Locatelli, Marcello: 1 article (12/2017)
9.	Menta, Sergio: 1 article (12/2017)
10.	Zengin, Gokhan: 1 article (12/2017)

Related Diseases

1.	Vulvovaginal Candidiasis 11/01/1999 - "Butoconazole 1-BSR rapidly relieved the signs and symptoms of vulvovaginal candidiasis. " 04/01/1988 - "Patient acceptance of a new, compact, prefilled disposable vaginal applicator was tested in an open study in which 2% butoconazole cream was used for the treatment of vulvovaginal candidiasis. " 11/01/1999 - "Butoconazole nitrate 2% for vulvovaginal candidiasis. " 05/01/1988 - "[Butoconazole nitrate in vulvovaginal candidiasis. " 07/04/1986 - "Butoconazole for vulvovaginal candidiasis."
2.	Candidiasis (Moniliasis) 01/01/1993 - "Efficacy of butoconazole nitrate in the treatment of vulvo-vaginal candidiasis compared with clotrimazol and isoconasol." 12/01/2012 - "Treatment of recurrent vulvo-vaginal candidiasis with sustained-released butoconazole pessary." 08/01/1985 - "In a single blind trial, a three day course of butoconazole nitrate cream was compared with a seven day course of miconazole nitrate cream, both applied intravaginally, in treating vaginal candidiasis. " 08/01/1985 - "Butoconazole and miconazole in treating vaginal candidiasis." 07/08/1996 - "Most responders (64%) agreed that pharmacists could provide, without a prescription, a 3-day course of a vaginal cream containing 2% butoconazole for vaginal candidiasis in nonpregnant women and a rectal suppository containing steroids for hemorrhoid sufferers (61%). "
3.	Neoplasms (Cancer) 11/09/2022 - "Herein, we examined two azole antifungal drugs, terconazole (TCZ) and butoconazole (BTZ), previously unexplored in resistant cancers. " 01/01/2000 - "In this study, we show that fluconazole-resistant (MIC > 64 microg/mL) blood stream isolates of Candida albicans and Candida glabrata obtained from cancer patients were cross-resistant to the root drugs miconazole, clotrimazole, and tioconazole (found in several over-the-counter products), but remained susceptible to butoconazole. "
4.	Pruritus (Itching) 12/01/2005 - "Vulvovaginal pruritus and vulvovaginal burning were the most common drug-related adverse events attributed to butoconazole. " 09/01/2006 - "The anti-inflammatory activities of eight anti-fungal agents (butoconazole, ciclopirox olamine, fluconazole, miconazole nitrate, sertaconazole nitrate, terconazole, tioconazole and ketoconazole) were compared in a number of preclinical models of dermal inflammation and pruritus. "
5.	Mycoses (Diseases, Fungus) 10/01/1984 - "Eight days after treatment completion, Candida albicans was absent in vaginal cultures of 95% of patients receiving butoconazole and of 91% of patients receiving clotrimazole; 30 days after treatment completion, 80% of patients receiving butoconazole were free of the fungal infection; the corresponding number for clotrimazole was 74%. " 12/01/2017 - "This paper reports the MEPS-HPLC-DAD method for the simultaneous determination of 12 azole drugs (bifonazole, butoconazole, clotrimazole, econazole, itraconazole, ketoconazole, miconazole, posaconazole, ravuconazole, terconazole, tioconazole and voriconazole) administered to treat different systemic and topical fungal infections, in biological samples. "

Related Drugs and Biologics

1.	Miconazole (Monistat)
2.	imidazole
3.	Clotrimazole (Lotrimin)
4.	Vaginal Creams, Foams, and Jellies (Vaginal Tablet)
5.	Econazole
6.	Fluconazole (Zonal)
7.	tioconazole
8.	Nystatin (Mycostatin)
9.	Tablets
10.	terconazole (Fungistat)

Related Therapies and Procedures

1.	Therapeutics
2.	Aftercare (After-Treatment)
3.	Pessaries