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aurin

structure

Also Known As:

rosolic acid; 4(bis(p-hydroxyphenyl)methylene)-2,5-cyclohexadien-1-one

Networked: 5 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Carbocyclic Acids
    - Cyclohexanecarboxylic Acids
      - Aurintricarboxylic Acid: 94
        aurin: 5

Experts

1.	Cabello, Christopher M: 1 article (01/2015)
2.	Davis, Angela L: 1 article (01/2015)
3.	Gokhale, Vijay: 1 article (01/2015)
4.	Lesson, Jessica L: 1 article (01/2015)
5.	Park, Sophia L: 1 article (01/2015)
6.	Qiao, Shuxi: 1 article (01/2015)
7.	Rojo de la Vega, Montserrat: 1 article (01/2015)
8.	Seanez, Carol M: 1 article (01/2015)
9.	Wondrak, Georg T: 1 article (01/2015)

Related Diseases

1.	Venous Thrombosis (Deep-Vein Thrombosis) 01/01/1997 - "In vivo anti-thrombotic studies in the hamster showed that the vWF antagonist aurin tricarboxylc acid was a more potent inhibitor of arterial thrombosis than of venous thrombosis, confirming the in vivo role of vWF during thrombus formation. "
2.	Thrombosis (Thrombus) 01/01/1997 - "In vivo anti-thrombotic studies in the hamster showed that the vWF antagonist aurin tricarboxylc acid was a more potent inhibitor of arterial thrombosis than of venous thrombosis, confirming the in vivo role of vWF during thrombus formation. "
3.	Typhoid Fever (Typhoid) 11/01/1951 - "[Results of the effectiveness of rosolic acid medium in differentiation of typhoid bacteria in water analysis]."
4.	Ocular Tuberculosis 02/01/1951 - "[Four cases of ocular tuberculosis treated with trimethoxy-aurin]."
5.	Melanoma (Melanoma, Malignant) 01/16/2015 - "Taken together, our data suggest feasibility of apoptotic elimination of malignant melanoma cells using the quinone methide-derived heat shock response inducer aurin. " 01/16/2015 - "Aurin-induced melanoma cell apoptosis depends on Noxa up-regulation as confirmed by siRNA rescue experiments demonstrating that siPMAIP1-based target down-regulation suppresses aurin-induced cell death. " 01/16/2015 - "Aurin exposure caused caspase-dependent cell death in a panel of human malignant melanoma cells (A375, G361, LOX-IMVI) but not in non-malignant human skin cells (Hs27 fibroblasts, HaCaT keratinocytes, primary melanocytes) undergoing the aurin-induced heat shock response without impairment of viability. " 01/16/2015 - "The quinone methide aurin is a heat shock response inducer that causes proteotoxic stress and Noxa-dependent apoptosis in malignant melanoma cells."

Related Drugs and Biologics

1.	Acids
2.	Small Interfering RNA (siRNA)
3.	Caspases
4.	Methacrylates
5.	Aurintricarboxylic Acid
6.	Aluminum
7.	quinone methide