11- nor- delta(9)- tetrahydrocannabinol- 9- carboxylic acid

RN given refers to cpd without isomeric designation; a major acidic metabolite of tetrahydrocannabinol in human urine

Also Known As:

(6aR-trans)-isomer of 11-nor-delta(9)-tetrahydrocannabinol-9-carboxylic acid; 11-nor-9-carboxy-THC; 11-nor-9-carboxy-delta(9)-tetrahydrocannabinol; 11-nor-9-carboxy-delta-9-tetrahydrocannabinol; THC-11-oic acid; delta(1)-tetrahydrocannabinol-7-oic acid; delta(9)-tetrahydrocannabinol-11-oic-acid; delta-9-11-carboxytetrahydrocannabinol; hexadeutero-11-nor-delta(9)-tetrahydrocannabinol-9-carboxylic acid; tetrahydrocannabinol-7-oic acid

Networked: 5 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Cannabinoids: 5901
      - Dronabinol: 2316
        11-nor-delta(9)-tetrahydrocannabinol-9-carboxylic acid: 5

Experts

1.	Bisconti, Mario: 1 article (01/2019)
2.	Busardò, Francesco Paolo: 1 article (01/2019)
3.	De Palma, Angela: 1 article (01/2019)
4.	Giacobbe, Raffaela: 1 article (01/2019)
5.	Martucci, Paola: 1 article (01/2019)
6.	Pacifici, Roberta: 1 article (01/2019)
7.	Pellegrini, Manuela: 1 article (01/2019)
8.	Pichini, Simona: 1 article (01/2019)
9.	Rotolo, Maria Concetta: 1 article (01/2019)
10.	Barnes, Allan J: 1 article (01/2016)

Related Diseases

1.	Marijuana Use 01/01/2012 - "Analysis of individual studies indicated that the heightened risk of crash involvement associated with marijuana use persisted after adjustment for confounding variables and that the risk of crash involvement increased in a dose-response fashion with the concentration of 11-nor-9-carboxy-delta-9-tetrahydrocannabinol detected in the urine and the frequency of self-reported marijuana use. " 01/01/2008 - "Gas chromatography mass/spectrometry quantitative analysis of 11-nor-9-carboxy-delta-9-tetrahydrocannabinol (THCCOOH), the major metabolite of delta-9-tetrahydrocannabinol (THC) found in urine following marijuana use, was performed on serial urine specimens collected from an inpatient adolescent population of marijuana users. "
2.	Substance-Related Disorders (Drug Abuse) 01/01/1982 - "THC-11-oic acid has been detected in urines collected after the smoking of one standard cigarette containing 16-18 mg of delta 9-tetrahydrocannabinol and in 34 of the first 100 tests of spontaneously collected urines of patients in a hospital drug-abuse treatment program. "
3.	Pruritus (Itching) 01/01/2016 - "Changes in the concentration of THC and its nonpsychotropic metabolite, 11-nor-9-carboxy-THC, were related to percent change from baseline of several descriptors (eg, itching, burning, and deep pain). "
4.	Pain (Aches) 01/01/2016 - "Changes in the concentration of THC and its nonpsychotropic metabolite, 11-nor-9-carboxy-THC, were related to percent change from baseline of several descriptors (eg, itching, burning, and deep pain). "
5.	Lung Diseases (Lung Disease) 01/01/2019 - "We developed and validated a method for the identification and quantification of cannabinol (CBN), cannabidiol (CBD), Δ-9-tetrahydrocannabinol (THC) and its metabolites 11-hydroxy-THC (11-OH-THC) and 11-nor-9-carboxy-THC (THC-COOH) in bronchoalveolar lavages (BALs) from hospitalized former or current tobacco smoking patients with lung disease and a long history of cannabis consumption and limited current tobacco use. "

Related Drugs and Biologics

1.	Dronabinol (THC)
2.	Cannabinol
3.	Cannabidiol