quinidine gluconate (Quinact)

07/13/1989 - "We conclude that the continuous infusion of quinidine gluconate is well tolerated alone and with exchange transfusion and is effective in the treatment of severe and complicated malaria."
01/01/2016 - "We look at the challenges experienced in the malaria Quinact trial, conducted in the Democratic Republic of Congo, and describe some lessons learned, related to the definition of acceptable representative, the role of independent witness and the impact of socio-economic vulnerability. "
08/01/1985 - "Study of IV quinidine gluconate for severe malaria."
04/01/2011 - "The only Federal Drug Administration approved treatment for severe malaria is intravenous quinidine gluconate. "
10/05/2004 - "Hospitals must maintain intravenous quinidine gluconate on formulary because it is the only drug available to treat severe malaria in the United States."

10/01/1994 - "Intravenous quinidine gluconate and exchange transfusion for malignant Plasmodium falciparum malaria."
11/01/1988 - "falciparum malaria with parenteral quinidine gluconate. "
05/01/1987 - "Continuous-infusion quinidine gluconate for treating children with severe Plasmodium falciparum malaria."
08/01/1985 - "Plasmodium falciparum malaria and intravenous quinidine gluconate."
05/16/1985 - "Quinidine gluconate is more widely available than quinine in many countries, and our findings show that it is effective in severe falciparum malaria."

09/15/1988 - "Eighteen patients with an accessory AV connection who had inducible sustained orthodromic tachycardia underwent an electrophysiologic study in the baseline state and after at least 2 days of treatment with 1.4 to 1.9 g/day of quinidine gluconate. "
07/01/1983 - "Quinidine gluconate (mean dose 9.1 +/- 1.6 mg/kg) was administered during electrophysiologic study to 100 patients with ventricular or supraventricular tachyarrhythmias. "

01/01/1989 - "Eight patients with previously untreated ventricular tachycardia, age 48.54 +/- 28.02 years (mean +/- SD), were enrolled in a protocol evaluating the disposition of quinidine gluconate as determined by two assay methods. "
01/01/1989 - "Comparison of disposition values obtained by two assay methods for quinidine gluconate in patients with ventricular tachycardia."
08/01/1988 - "Twenty-one patients with coronary artery disease and a history of unimorphic ventricular tachycardia were found to have inducible sustained unimorphic ventricular tachycardia that was suppressed by treatment with oral quinidine gluconate. "
07/01/1998 - "Seven (22%) patients assigned to intravenous quinidine gluconate and eight (24%) patients assigned to intravenous procainamide hydrochloride were rendered noninducible for ventricular tachyarrhythmias. "
07/01/1998 - "Sixty-five consecutive patients with inducible ventricular tachyarrhythmias were prospectively treated with either intravenous quinidine gluconate or intravenous procainamide hydrochloride in an alternating unblinded fashion. "

04/12/1991 - "falciparum infections is parenteral quinidine gluconate. "
06/21/1985 - "Intravenous quinidine gluconate in the treatment of severe Plasmodium falciparum infections."
04/19/1991 - "falciparum infection is parenteral quinidine gluconate, and that stocking of parenteral quinine dihydrochloride for emergency distribution is no longer required to provide optimal management of P. "
04/19/1991 - "Treatment with quinidine gluconate of persons with severe Plasmodium falciparum infection: discontinuation of parenteral quinine from CDC Drug Service."
11/01/1993 - "Although quinine historically has been the mainstay of therapy for severe falciparum malaria in the United States, and still is outside the U.S., quinidine gluconate as a continuous infusion is currently recommended as the agent of choice for severe P falciparum infection. "