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poly(2'-O-methylcytidylic acid)
Also Known As:
poly(2'-methylcytidilate); poly(rCm)
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Nucleic Acids, Nucleotides, and Nucleosides: 1
Nucleotides: 15763
Polynucleotides: 218
Polyribonucleotides: 23
Poly C: 296
poly(2'-O-methylcytidylic acid): 1
Related Diseases
1.
Breast Neoplasms (Breast Cancer)
02/01/1977 - "
Thus like these viral enzymes, the purified human breast cancer DNA polymerase exhibits the following three features that together distinguish the known viral reverse transcriptases from normal cellular DNA polymerases: (i) a strong preference for oligo(dT)-poly(rA) over oligo(dT)-poly(dA) as a template for the synthesis of poly(dT); (ii) the acceptance of the highly specific oligo(dG)-poly(rCm) as a template for the formation of poly(dG); (iii) the ability to use a viral RNA (AMV) as a template to fashion a faithful DNA complementary copy; and (iv) its preference for Mg++ over Mn++.
"
Related Drugs and Biologics
1.
Complementary DNA (cDNA)
2.
Viral RNA
3.
DNA-Directed RNA Polymerases (RNA Polymerase)
4.
Poly T
5.
Poly A
6.
Enzymes
7.
DNA-Directed DNA Polymerase (Polymerases, DNA)
8.
oligodeoxyguanylic acid
9.
oligo (dT)
10.
poly(dG)